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TRIS-HCl
CAS:No.1185-53-1
分子式:C4H12ClNO3
分子量:157.64
储存条件:RT，有效期7年
纯度:≥99.5%
英文名称:Tris (Hydroxymethyl) Aminomethane Hydrochloride
产品简介
| 别名 | 盐酸三(羟甲基)氨基甲烷； 2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride；TRIS hydrochloride； Tromethane hydrochloride。 |
| 英文名称 | Tris (Hydroxymethyl) Aminomethane Hydrochloride |
| CAS | No.1185-53-1 |
| 分子式 | C4H12ClNO3 |
| 分子量 | 157.64 |
| 储存条件 | RT，有效期7年 |
| 外观(性状) |
白色结晶粉末
|
| 级别 | Ultra Pure Grade |
| 纯度 | ≥99.5% |
| 溶解性 | 667mg/ml in water |
| 危险代码 | 36/37/38 |
| 规格 | 100g 500g |
| 单位 | 瓶 |
说明书：缓冲剂。
中文名称：三羟甲基氨基甲烷盐酸盐
英文名称：Tris(hydroxymethyl)aminomethane hydrochloride
CAS:1185-53-1
分子式：C4H11NO3•HCL
分子量：157.60
等级：生化级
质量标准：
外观：白色结晶
含量：≥99.0％
熔点：150.0-153.0℃
Residue on Ignition：≤0.1％
水溶性：清澈
水分：≤0.5％
PH(1.0mol/L)：3.7-4.7
PKa(20℃)：8.0-8.4
产品应用：Tris-HCL缓冲液不仅被广泛用作核酸和蛋白质的溶剂，还有许多重要用途。Tris-HCL被用于不同pH条件下的蛋白质晶体生长。[3]Tris-HCL缓冲液的低离子强度特点可用于线虫（C. elegans）核纤层蛋白（lamin）的中间纤维的形成。[4]Tris-HCL也是蛋白质电泳缓冲液的主要成分之一。此外，Tris-HCL还是制备表面活性剂、硫化促进剂和一些药物的中间物。Tris-HCL也被用作滴定标准物。
备注：产品信息可能会有优化升级。请以实际标签信息为准。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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Neutrophil membrane-coated nanoparticles for targeted delivery of toll-like receptor 4 siRNA ameliorate LPS-induced acute lung injury
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Author：
Liang Cao, Min Du, Mengmeng Cai, Yan Feng, Juanjuan Miao, Jiafeng Sun, Jie Song, Boxiang Du
IF：
5.3000
Publish_to：
INTERNATIONAL JOURNAL OF PHARMACEUTICS
PMID：
39551221
Screening and validation of quorum quenching enzyme PF2571 from Pseudomonas fluorescens strain PF08 to inhibit the spoilage of red sea bream filets
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Author：
Dangfeng Wang, Haitao Chen, Jianrong Li, Tingting Li, Likun Ren, Jingyun Liu, Yue Shen
IF：
5.2770
Publish_to：
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
PMID：
34798478
A polypyrrole-mediated photothermal biosensor with a temperature and pressure dual readout for the detection of protein biomarkers
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Author：
Eunyeong Song, Yingzhou Tao, Haicong Shen, Chaoyong Yang, Tian Tian, Liu Yang, Zhi Zhu
IF：
5.2270
Publish_to：
ANALYST
PMID：
35593135
Temperature sensitive liposome based cancer nanomedicine enables tumour lymph node immune microenvironment remodelling
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Author：
Chao Ji, Yihan He, Xiangfu Xu, Jinxin Liu, Wei Liu, Xingyu Wang, Liangjuan Zhao, Wenjie Zheng, Xiaonan Lu
IF：
5.2000
Publish_to：
Food Bioscience
PMID：
Synergy of “Yiqi” and “Huoxue” components of QishenYiqi formula in ischemic stroke protection via lysosomal/inflammatory mechanisms
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Author：
Yule Wang, Xinyan Liu, Wen Zhang, Shuang He, Yiqian Zhang, John Orgah, Yi Wang, Yan Zhu
IF：
5.1950
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
35436536
Inhibition of cytochrome P450 enzymes and uridine 5′-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions
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Author：
Shuaibing Liu, Ziteng Wang, Eric Chan, Yibo Zhao, Jian Kang, Xiaojian Zhang, Xin Tian
IF：
5.1940
Publish_to：
CHEMICO-BIOLOGICAL INTERACTIONS
PMID：
34910929
Preparation and Characterization of Protein Molecularly Imprinted Poly (Ionic Liquid)/Calcium Alginate Composite Cryogel Membrane with High Mechanical Strength for the Separation of Bovine Serum Albumin
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Author：
Jie-Ping Fan, Wen-Ya Dong, Xue-Hong Zhang, Jia-Xin Yu, Cong-Bo Huang, Li-Juan Deng, Hui-Ping Chen, Hai-Long Peng
IF：
4.9270
Publish_to：
MOLECULES
PMID：
36364136
Exploring the Impact of Pharmaceutical Excipient PEG400 on the Pharmacokinetics of Mycophenolic Acid Through In Vitro and In Vivo Experiments
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Author：
Chaoji Li, Min Zhang, Yanni Zhao, Dan Yang, Mei Zhao, Leyuan Shang, Xiaodong Sun, Shuo Zhang, Pengjiao Wang, Xiuli Gao
IF：
4.9000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
39795931
Molecular interactions between bovine serum albumin (BSA) and trihalophenol: Insights from spectroscopic, calorimetric and molecular modeling studies
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Author：
Wenjie Liang, Zhenxuan Zhang, Qingyao Zhu, Zekun Han, Cui Huang, Xiong Liang, Mengting Yang
IF：
4.8310
Publish_to：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
PMID：
36334416
A Nanobody of PEDV S1 Protein: Screening and Expression in Escherichia coli
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Author：
Zhipeng Hao, Xufeng Dong, Zhongtao Zhang, Zhihua Qin
IF：
4.8000
Publish_to：
Biomolecules
PMID：
39334881
The miR-665/SOST Axis Regulates the Phenotypes of Bone Marrow Mesenchymal Stem Cells and Osteoporotic Symptoms in Female Mice
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Author：
Xingxing Zeng, Xianyu Yuan, Hongchun Liao, Yongfang Wei, Qinxuan Wu, Xi Zhu, Qingqing Li, Shijie Chen, Minghua Hu
IF：
4.7000
Publish_to：
AMERICAN JOURNAL OF PATHOLOGY
PMID：
39461772
Trehalose 6-Phosphate/SnRK1 Signaling Participates in Harvesting-Stimulated Rubber Production in the Hevea Tree
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Author：
Binhui Zhou, Yongjun Fang, Xiaohu Xiao, Jianghua Yang, Jiyan Qi, Qi Qi, Yujie Fan, Chaorong Tang
IF：
4.6580
Publish_to：
Plants-Basel
PMID：
36365332
Identification of zebrafish PLEKHF2 presents in egg/embryos as an antibacterial protein
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Author：
Yiqing Ren, Chunqiu Wang, Hao Wang, Qingqi Chang, Dongqiu Guo, Xia Wang
IF：
4.6220
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
35863537
Cellulose nanocrystals supported ternary alloy nanoclusters catalysts for efficient hydrogen production from formic acid
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Author：
Kuangyin Chen, Yanqiu Liang, Zhiwei Hu, Jianhua Shen
IF：
4.6000
Publish_to：
Molecular Catalysis
PMID：
Bone-Targeted Dual Functional Lipid-coated Drug Delivery System for Osteosarcoma Therapy
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Author：
Zhong Jie, Wen Weiye, Wang Jinjin, Zhang Mengyu, Jia Yijiang, Ma Xiaowei, Su Yu-xiong, Wang Yuji, Lan Xinmiao
IF：
4.5800
Publish_to：
PHARMACEUTICAL RESEARCH
PMID：
36380167
Development of S4A–BSA–Au NPs for enhanced anti-tumor therapy of canine breast cancer
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Author：
Qi Chen, Chengfang Xu, Zhonghao Sun, Jingjing Yang, Fan Chen, Zixiang Lin, Degui Lin, Yanyan Jiang, Jiahao Lin
IF：
4.5530
Publish_to：
Nanoscale Advances
PMID：
36132165
Assessing the double-edged of extracellular signal-regulated kinase/CCAAT-enhancer-binding protein beta signaling pathway in arsenic-induced skin damage and its potential foodborne interventions
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Author：
Fan Yang, Dexiu Hu, Sufei Du, Liping Wu, Maoyuan Gong, Yuhong Zhang, Xingcan Yang, Yang Yang, Ruobi Chen, Yuyan Xu, Qibing Zeng
IF：
4.5000
Publish_to：
ENVIRONMENTAL TOXICOLOGY
PMID：
37565747
Preparation of Hybrid Magnetic Nanoparticles for Sensitive and Rapid Detection of Phorate Residue in Celery Using SERS Immunochromatography Assay
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Author：
Xiangyang Li, Hean Qian, Jin Tao, Mingshuo Cao, Meng Wang, Wenlei Zhai
IF：
4.4000
Publish_to：
Nanomaterials
PMID：
38921922
Durable 3D Porous Superhydrophobic Composites for Versatile Emulsion Separation in Multiple Environments
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Author：
Qinghong Zeng, Jiaxu Zhang, Siyang Zhao, Hao Yue, Jinxia Huang, Zhiguang Guo, Weimin Liu
IF：
4.3310
Publish_to：
LANGMUIR
PMID：
36169614
Crazing Effect on the Bio-Based Conducting Polymer Film
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Author：
Pei-Yi Wong, Akiyoshi Takeno, Shinya Takahashi, Sook-Wai Phang, Azizah Baharum
IF：
4.3290
Publish_to：
Polymers
PMID：
34641240
Effects of codon optimization, N-terminal truncation and gene dose on the heterologous expression of berberine bridge enzyme
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Author：
Xu Zixuan, Xia Liqiong, Sun Mengshan, Huang Peng, Zeng Jianguo
IF：
4.2530
Publish_to：
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
PMID：
35316417
Rapid Detection of Alpha-Fetoprotein (AFP) with Lateral Flow Aptasensor
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Author：
Meijing Ma, Min Zhang, Jiahui Wang, Yurui Zhou, Xueji Zhang, Guodong Liu
IF：
4.2000
Publish_to：
MOLECULES
PMID：
39942588
Simple Monovalent Metal Ion Logical Order to Regulate the Secondary Conformation of G-Quadruplex
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Author：
Xin Tong, Lu Ga, Chaolu Eerdun, Ruiguo Zhao, Jun Ai
IF：
4.1320
Publish_to：
ACS Omega
PMID：
36340069
Construction of a non-enzymatic electrochemical sensor based on graphitic carbon nitride nanosheets for sensitive detection of procalcitonin
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Author：
Yushuang Liu, Furong Chen, Layue Bao, Wenfeng Hai
IF：
4.0360
Publish_to：
RSC Advances
PMID：
36105974
The Long Noncoding RNA Hepatocyte Nuclear Factor 4α Antisense RNA 1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications
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Author：
Pei Wang, Shitong Chen, Yiting Wang, Xiaofei Wang, Liang Yan, Kun Yang, Xiao-bo Zhong, Shengna Han, Lirong Zhang
IF：
3.9220
Publish_to：
DRUG METABOLISM AND DISPOSITION
PMID：
33674270
Comparative Study on the Lubrication Mechanism and Performance of Two Representative Ionic and Nonionic Self-Adhesive Polymer Coatings
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Author：
Yiran Jia, Yinuo Yang, Hongyu Zhang
IF：
3.9000
Publish_to：
LANGMUIR
PMID：
38557053
New insights in the low-temperature-dependent formation of amorphous titania-coated magnetic polydopamine nanocomposites for the adsorption of methylene blue
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Author：
Zhang Jiangqun, Long Xingyu, Hu Meng, Wei Wanli, Gong Jiangning, Yang Chun, Xia Pinhua, Wang Anping
IF：
3.8000
Publish_to：
Scientific Reports
PMID：
39779769
In Vitro Evaluation of DNA Damage Effect Markers toward Five Nitrogen Mustards Based on Liquid Chromatography–Tandem Mass Spectrometry
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Author：
Kexin Li, Zehua Li, Jianfeng Wu, Ying Gong, Lei Guo, Jianwei Xie
IF：
3.7390
Publish_to：
CHEMICAL RESEARCH IN TOXICOLOGY
PMID：
34969250
Identification and Functional Analysis of PR Genes in Leaves from Variegated Tea Plant (Camellia sinensis)
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Author：
Zuguo Xi, Huiyan Jia, Yifan Li, Jinqing Ma, Mengqian Lu, Zhihui Wang, Dexu Kong, Wei-Wei Deng
IF：
3.7000
Publish_to：
Agronomy-Basel
PMID：
Porous-nanozyme-based colorimetric sensor for rapid detection of kanamycin in foods under neutral condition
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Author：
Wenying Zou, Junjun Wang, Siyi Yang, Yue Tang, Xiaojuan Niu, Yuangen Wu
IF：
3.6930
Publish_to：
JOURNAL OF FOOD SCIENCE
PMID：
37043597
Enhanced osteogenesis and antibacterial activity of dual-functional PEEK implants via biomimetic polydopamine modification with chondroitin sulfate and levofloxacin
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Author：
Mengjue Li, Junyan Liu, Yutong Li, Wenyu Chen, Zhou Yang, Yayu Zou, Yi Liu, Yue Lu, Jianfei Cao
IF：
3.6000
Publish_to：
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
PMID：
39155420
A signal-on fluorescent biosensor for mercury detection based on a cleavable phosphorothioate RNA fluorescent probe and metal–organic frameworks
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Author：
Yang Mei, Si Yang, Chenxi Li, Wenliang Chen, Rong Liu, Kexin Xu
IF：
3.5320
Publish_to：
Analytical Methods
PMID：
36300422
LncRNA OIP5-AS1 affects the biological behaviors of chondrocytes of patients with osteoarthritis by regulating micro-30a-5p
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Author：
G.-H. Qin, W.-C. Yang, J.-N. Yao, Y. Zhao, X.-J. Wu
IF：
3.5070
Publish_to：
European Review for Medical and Pharmacological Sciences
PMID：
33629291
ARMCX3 regulates ROS signaling, affects neural differentiation and inflammatory microenvironment in dental pulp stem cells
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Author：
Quanying Zhou, Yi Lei
IF：
3.4000
Publish_to：
Heliyon
PMID：
39296219
Nanochannel-based sensor for the detection of lead ions in traditional Chinese medicine
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Author：
Jiyuan Tu, Zhongshi Zhou, Yanju Liu, Tingxian Li, Shumin Lu, Ling Xiao, Pingping Xiao, Guojun Zhang, Zhongyue Sun
IF：
3.3610
Publish_to：
RSC Advances
PMID：
35424271
Sulfur Amino Acid Metabolism and the Role of Endogenous Cystathionine-γ-lyase/H2S in Holstein Cows with Clinical Mastitis
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Author：
Bohao Zhang, Ting Lin, Xu Bai, Xiaoxiao An, Lijun Dai, Jun Shi, Yong Zhang, Xingxu Zhao, Quanwei Zhang
IF：
3.2310
Publish_to：
Animals
PMID：
35681915
Synthesis of N,Si co-doped carbon dots to establish a fluorescent sensor for Hg(II) detection with triple signal output
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Author：
Jun Zhou, Chengyue Zou, Danqun Huo, Chengxiang Chu, Shasha Liu, Mei Yang, Suyi Zhang, Xianfeng Wang, Changjun Hou
IF：
3.1000
Publish_to：
Analytical Methods
PMID：
37767981
Light Controlled Nanobiohybrids for Modulating Chiral Alcohol Synthesis
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Author：
Yin Hang, Cui Shitong, Cao Yufei, Ge Jun, Lou Wenyong
IF：
3.0000
Publish_to：
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
PMID：
37594649
The pharmaceutical excipient PEG400 affect the absorption of baicalein in Caco-2 monolayer model by interacting with UDP-glucuronosyltransferases and efflux transport proteins
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Author：
Siyuan Cao, Min Zhang, Minyan Yuan, Dan Yang, Mei Zhao, Shuo Zhang, Pengjiao Wang, Rongping Zhang, Xiuli Gao
IF：
2.9630
Publish_to：
Pharmacology Research & Perspectives
PMID：
35148019
Apoptotic bodies encapsulating Ti2N nanosheets for synergistic chemo-photothermal therapy
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Author：
Kuo Yang, Daolu Ren, Zuyao Wang, Qianqian Dong, Mulong Xu, Tingyu Wang, Zhuyuan Wang
IF：
2.9000
Publish_to：
NANOTECHNOLOGY
PMID：
38861968
The Distribution, Expression Patterns and Functional Analysis of NR1D1 and NR4A2 in the Reproductive Axis Tissues of the Male Tianzhu White Yak
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Author：
Lijun Dai, Quanwei Zhang, Jun Shi, Xu Bai, Xiaoxiao An, Bohao Zhang, Yong Zhang, Xingxu Zhao
IF：
2.7520
Publish_to：
Animals
PMID：
34827849
Barley Leaf Ameliorates Citrobacter-rodentium-Induced Colitis through Arginine Enrichment
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Author：
Yao-Meng Huang, Tong-Xin Li, Shu-Yu Li, Xiao-Ran Zhu, Ying Li, Dang-Yang Liu, Wei-Min Li, Lin-Quan Yang, Kun-Shen Liu, Chao Liu
IF：
2.7000
Publish_to：
Experimental and Therapeutic Medicine
PMID：
37415837
Unveiling the Pharmacological Role of Human Deubiquitinating Enzymes in Temozolomide Response of Glioblastoma Cells
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Author：
Yang Chunguang, Li Yifei, Wu Qifan, Tang Jiayi, Chen Min, Zhang Baoyu, Li Bowen, Qin Yunfei, Huang Guobin, Zhang Yize, Zhi Feng, Liu Kunpeng
IF：
2.6000
Publish_to：
CELL BIOCHEMISTRY AND BIOPHYSICS
PMID：
38809352
Dectin-1 deficiency alleviates diabetic cardiomyopathy by attenuating macrophage-mediated inflammatory response
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Author：
Wang Di, Xing Pei-Xiang, Diao Hong-Liang, Zhou Wen-Wen, Li Xian-Wei, Zhang Li-Jun, Ma Rui-Yan
IF：
2.5000
Publish_to：
BIOCONTROL
PMID：
Dexamethasone and azithromycin enhance goat sperm preservation quality by regulating lipid metabolism
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Author：
Yongjie Xu, Shixin Sun, Mingyue Wang, Wenzheng Shen, Lei Wang, Chunhuan Ren, Yinghui Ling, Zijun Zhang, Hongguo Cao
IF：
2.4000
Publish_to：
THERIOGENOLOGY
PMID：
39476552
Label-free fluorescence displacement sensors based on split aptamers and Thioflavin T for the rapid and sensitive detection of kanamycin in milk
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Author：
Xinyue Yin, Qi Pu, Chumeng Wang, Yuhong Xiang, Nengsheng Ye
IF：
2.3000
Publish_to：
Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
PMID：
39899703
A rapid and efficient one-step site-directed deletion, insertion, and substitution mutagenesis protocol
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Author：
Deguang Wu Xuewu Guo Jun Lu Xi Sun Feng Li Ye
IF：
2.2750
Publish_to：
Analytical Biochemistry
PMID：
23256925
EGCG promotes the sensory function recovery in rats after dorsal root crush injury by upregulating KAT6A and inhibiting pyroptosis
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Author：
Jianjun Wang, Zuer Yu, Yichun Hu, Fuyu Li, Xiaoyu Huang, Xiangyue Zhao, Yaqi Tang, Shujuan Fang, Yinjuan Tang
IF：
2.1000
Publish_to：
Translational Neuroscience
PMID：
38152093
Effects of demineralization mode and particle size of allogeneic bone powder on its physical and chemical properties
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Author：
Song Kun-xiu, Ji Shao-lin, Zhao Yong-jie, Zhang Hao-ran, Ma Rong-xing, Zhang Jing-yu, Hu Yong-cheng
IF：
1.7520
Publish_to：
CELL AND TISSUE BANKING
PMID：
35831637
Insight into the thrombolytic ability of an extracellular fibrinolytic enzyme from Bacillus amyloliquefaciens GXU-1 isolated from Sipunculus nudus
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Author：
Hongrui Jiang, Ruiyuan Shi, Xiaomei Li, Jiale Tang, Douyong Min
IF：
1.6000
Publish_to：
PROTEIN EXPRESSION AND PURIFICATION
PMID：
37709210
Rapid Separation and Display of Active Fibrinogenolytic Agents in Sipunculus nudus through Fibrinogen-Polyacrylamide Gel Electrophoresis
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Author：
Bin Kang, Chengjia Hu, Hongjun Lin, Hui Yan, Chengyun Wei, Mingqing Tang
IF：
1.2000
Publish_to：
Jove-Journal of Visualized Experiments
PMID：
38709073
技术问答
（3）
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
京公网安备 11011202000391号
能否直接溶解配制TBS缓冲液(PH7,4)?2023-05-19 12:39:44
您好，T8230不用于直接配制TBS缓冲液；配制TBS缓冲液可以看一下货号T1083、T1084、T1080，PH可以根据自己要求用盐酸调节。
咱这Tris-Hcl是药用级的吗?2022-11-29 16:22:54
您好，不是医药级的。
这个粉末怎么配Tris-HCL PH8.8 和PH6.8的液体?2022-08-09 18:40:08
您好，Tris-HCL PH8.8 和PH6.8的使用T8060 Tris碱溶解需要的浓度后用浓盐酸调到实验要求的PH值，不建议用T8230来配。