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全蛋白提取试剂盒（强）
英文名称:Total Protein Extraction Maxi kit
储存条件:-20℃，avoid light，at least 1 year
产品简介
| 英文名称 | Total Protein Extraction Maxi kit |
| 中文名称 | 全蛋白提取试剂盒（强） |
| 储存条件 | -20℃，avoid light，at least 1 year |
| 规格 | 50T 100T |
| 单位 | 盒 |
全蛋白提取试剂盒（强）用于哺乳动物组织和细胞中提取总蛋白，试剂盒中的裂解液含有蛋白酶抑制剂和磷酸酶抑制剂，作用较为强烈，可快速获得总蛋白，可用于免疫印迹实验等基础研究实验，由于含有上述的酶抑制剂，不能用于研究蛋白激酶和磷酸激酶的研究。本品仅用于科研。
产品组成:
产品组成:
| 试剂名称 | 规格 | 储存条件 |
| 裂解液（强） | 100mL | 2-8℃ |
| 磷酸酶抑制剂（100×） | 1mL | -20℃ |
| 蛋白酶抑制剂（100×） | 1mL | |
| PMSF（100×） | 1mL |
操作方法:
1、组织总蛋白的提取
在1ml的冷裂解液中各加入10ul的磷酸酶抑制剂、蛋白酶抑制剂和PMSF；混匀，放置在冰上备用；
称取0.1g的新鲜组织，放置于玻璃匀浆器的入口缓冲处，用眼科剪将组织块尽可能的剪碎，然后加入0.5-1ml的新配置的裂解液，研磨直至没有明显的组织块，这个过程注意冰上操作；
将组织匀浆液移入1.5ml的EP管中，4 oC 12000g离心30min；
吸取上清至新的管中；
进行蛋白定量或者变性进行蛋白实验。
（提取好的蛋白建议保存于-80 oC，即用即取，避免反复冻融，避免长时间储存。)
2、细胞总蛋白的提取
裂解液的用量：107个细胞需要裂解液1ml；
贴壁细胞：弃去培养基，用冷的PBS洗两次，弃去PBS，然后加入计算好的细胞裂解液；在冰上用细胞刮刀进行刮离细胞，
将刮离的细胞裂解液移入EP管中，颠倒裂解20-30min
悬浮细胞：4 oC 400g离心收集细胞，用冷的PBS洗两次细胞，同样按细胞数加入裂解液，
涡旋10s，放置冰上裂解10min，重复3-4次；
裂解完毕之后，将细胞裂解液4 oC 12000g离心30min；
将上清移入新的EP管中；
进行蛋白定量或者变性进行蛋白实验。
（提取好的蛋白建议保存于-80 oC，即用即取，避免反复冻融，避免长时间储存。)
注意事项：
实验过程，所有试剂都要需要预冷或者即融，保证操作过程中的低温环境；
PSMF（有毒）现用现加，因为PMSF在水溶液中会快速降解；
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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38724500
Construction of Glucose-6-Phosphate Dehydrogenase Overexpression Strain of Schizochytrium sp. H016 to Improve Docosahexaenoic Acid Production
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Author：
Yumei Feng, Yuanmin Zhu, Zhendong Bao, Bohan Wang, Tingting Liu, Huihui Wang, Tianyi Yu, Ying Yang, Longjiang Yu
IF：
6.0850
Publish_to：
Marine Drugs
PMID：
36662190
Effect of Lactobacillus fermentum ZS40 on the NF-κB signaling pathway in an azomethane-dextran sulfate sodium-induced colon cancer mouse model
点击查看 >>
Author：
Jia Liu, Shuaiqi Wang, Ruokun Yi, Xingyao Long, Xin Zhao
IF：
6.0640
Publish_to：
Frontiers in Microbiology
PMID：
36225358
Exploring the Multi-Tissue Crosstalk Relevant to Insulin Resistance Through Network-Based Analysis
点击查看 >>
Author：
Yang Linlin, Yang Linquan, Wang Xing, Xing Hanying, Zhao Hang, Xing Yuling, Zhou Fei, Wang Chao, Song Guangyao, Ma Huijuan
IF：
6.0550
Publish_to：
Frontiers in Endocrinology
PMID：
35116003
Bacillus amyloliquefaciens B10 inhibits aflatoxin B1-induced cecal inflammation in mice by regulating their intestinal flora
点击查看 >>
Author：
Jia Chen, Zhiming Lv, Ziyang Cheng, Tiancheng Wang, Peng Li, Aibo Wu, Eugenie Nepovimova, Miao Long, Wenda Wu, Kamil Kuca
IF：
6.0250
Publish_to：
FOOD AND CHEMICAL TOXICOLOGY
PMID：
34303774
Astragalus Total Saponins Ameliorate Peritoneal Fibrosis by Promoting Mitochondrial Synthesis and Inhibiting Apoptosis
点击查看 >>
Author：
Zheng-Hong Li, Rong Xu, Jun Shi, Man-Shu Yu, Yu Zhong, Wei-Ming He, Li-Ping Cao, Mei-Xiao Sheng
IF：
6.0050
Publish_to：
AMERICAN JOURNAL OF CHINESE MEDICINE
PMID：
34983328
Sodium Danshensu ameliorates cerebral ischemia/reperfusion injury by inhibiting CLIC4/NLRP3 inflammasome-mediated endothelial cell pyroptosis
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Author：
Xiaolu Zhang, Qiuyue Yang, Ruifeng Zhang, Yilin Zhang, Wenyun Zeng, Qun Yu, Miao Zeng, Jiali Gan, Huhu Li, Lin Yang, Qing Gao, Xijuan Jiang
IF：
6.0000
Publish_to：
BIOFACTORS
PMID：
37458329
The effects of fresh Gastrodia elata Blume on the cognitive deficits induced by chronic restraint stress
点击查看 >>
Author：
Huang Hong, Zhang Yiwen, Yao Caihong, He Qinghu, Chen Fang, Yu Han, Lu Guanghua, Jiang Ning, Liu Xinmin
IF：
5.9880
Publish_to：
Frontiers in Pharmacology
PMID：
36105220
Macrophages-Related Genes Biomarkers in the Deterioration of Atherosclerosis
点击查看 >>
Author：
Yue Zheng, Bingcai Qi, Wenqing Gao, Zhenchang Qi, Yanwu Liu, Yuchao Wang, Jianyu Feng, Xian Cheng, Zhiqiang Luo, Tong Li
IF：
5.8460
Publish_to：
Frontiers in Cardiovascular Medicine
PMID：
35845072
AREG is involved in scleral remodeling in form-deprivation myopia via the ERK1/2-MMP-2 pathway
点击查看 >>
Author：
Man She, Tao Li, Wenqing Shi, Bing Li, Xiaodong Zhou
IF：
5.8340
Publish_to：
FASEB JOURNAL
PMID：
35436023
A Comprehensive Analysis of Metabolomics and Transcriptomics Reveals Novel Biomarkers and Mechanistic Insights on Lorlatinib Crosses the Blood-Brain Barrier
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Author：
Chen Wei, Li Chunyu, Shi Yafei, Zhang Yujun, Jin Dujia, Zhang Mingyu, Bo Mingming, Li Guohui
IF：
5.8110
Publish_to：
Frontiers in Pharmacology
PMID：
34497521
Inhibitory effect of Portulaca oleracea L. aqueous extract and juice on NLRP3 inflammasome activation in an ulcerative colitis mouse model
点击查看 >>
Author：
Fan Yi-meng, Wei Yuan-yuan, Wang Hui-ru, Yu-Ga, Zhang Yan-nan, Hao Zhihui
IF：
5.8000
Publish_to：
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
PMID：
37402916
Genome-wide map of N6-methyladenosine circular RNAs identified in mice model of severe acute pancreatitis
点击查看 >>
Author：
Jun Wu, Xiao-Hui Yuan, Wen Jiang, Yi-Chen Lu, Qi-Lin Huang, Yi Yang, Hua-Ji Qie, Jiang-Tao Liu, Hong-Yu Sun, Li-Jun Tang
IF：
5.7420
Publish_to：
WORLD JOURNAL OF GASTROENTEROLOGY
PMID：
34887647
CTRP3 alleviates myocardial ischemia/reperfusion injury in mice through activating LAMP1/JIP2/JNK pathway
点击查看 >>
Author：
Yanbin Song, Yunqing Zhang, Zhaofei Wan, Junqiang Pan, Feng Gao, Fei Li, Jing Zhou, Junmin Chen
IF：
5.7140
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
35278832
Medulla oblongata and NCCs are central defenders against Streptococcus agalactiae infection of the tilapia brain
点击查看 >>
Author：
Hou Xitan, Li Qi
IF：
5.7000
Publish_to：
Frontiers in Immunology
PMID：
39011038
miR-545 promotes colorectal cancer by inhibiting transferring in the non-normal ferroptosis signaling
点击查看 >>
Author：
Sixin Zheng, Lingling Hu, Qingwen Song, Yuqiang Shan, Guang Yin, Hanzhang Zhu, Wencheng Kong, Chunhua Zhou
IF：
5.6820
Publish_to：
Aging-US
PMID：
34954694
DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice
点击查看 >>
Author：
Zhu Ying, Wang Xinru, Zhou Xiaoyun, Ding Lexi, Liu Dan, Xu Huizhuo
IF：
5.6120
Publish_to：
BIOLOGICAL RESEARCH
PMID：
34362460
Methamphetamine exposure drives cell cycle exit and aberrant differentiation in rat hippocampal-derived neurospheres
点击查看 >>
Author：
Shaomin Wang, Liang Wang, Qian Bu, Qian Wei, Linhong Jiang, Yanping Dai, Ni Zhang, Weihong Kuang, Yinglan Zhao, Xiaobo Cen
IF：
5.6000
Publish_to：
Frontiers in Pharmacology
PMID：
37795025
The interaction between the lemon ribosomal protein ClRPS9-2 and citrus yellow vein clearing virus coat protein affects viral infection and gene silencing suppressor activity
点击查看 >>
Author：
Ting Zeng, Ping Liao, Cairong Zheng, Haixing Gao, Xiao Ye, Changyong Zhou, Yan Zhou
IF：
5.5200
Publish_to：
MOLECULAR PLANT PATHOLOGY
PMID：
37148475
Peripheral cytokine interleukin-10 alleviates perihematomal edema after intracerebral hemorrhage via interleukin-10 receptor/JAK1/STAT3 signaling
点击查看 >>
Author：
Yao Xu, Kaishan Wang, Yalan Dai, Wei Yang, Xufang Ru, Wenyan Li, Hua Feng, Gang Zhu, Qin Hu, Yujie Chen
IF：
5.5000
Publish_to：
CNS Neuroscience & Therapeutics
PMID：
38867395
Panax notoginseng saponin alleviates pulmonary fibrosis in rats by modulating the renin-angiotensin system
点击查看 >>
Author：
Han Li, Yu-guang Wang, Teng-fei Chen, Yun-hang Gao, Ling Song, Yi-fei Yang, Yue Gao, Wang Huo, Guang-ping Zhang
IF：
5.4000
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
37532070
Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway
点击查看 >>
Author：
Yuqiang Shan, Jiaotao Li, Akao Zhu, Wencheng Kong, Rongchao Ying, Weiming Zhu
IF：
5.3140
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
PMID：
35582998
miR-940 modulates CD47 to suppress biological functions of lung adenocarcinoma cells
点击查看 >>
Author：
Shuzi Long, Xizi Long, Jing Guo, Liping Fu, Xiaoping Huang, Huawen Liu
IF：
5.3000
Publish_to：
American Journal of Cancer Research
PMID：
38590419
Larotrectinib induces autophagic cell death through AMPK/mTOR signalling in colon cancer
点击查看 >>
Author：
Wencheng Kong, Hangzhang Zhu, Sixing Zheng, Guang Yin, Panpan Yu, Yuqiang Shan, Xinchun Liu, Rongchao Ying, Hong Zhu, Shenglin Ma
IF：
5.2950
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
36251949
Mechanism underlying Polygonum capitatum effect on Helicobacter pylori-associated gastritis based on network pharmacology
点击查看 >>
Author：
Xiaohan Song, Yun He, Min Liu, Ye Yang, Yan Yuan, Jiaoyan Yan, Mengwei Zhang, Jian Huang, Shu Zhang, Fei Mo
IF：
5.2750
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
34157554
Hypoxia impairs male reproductive functions via inducing rat Leydig cell ferroptosis under simulated environment at altitude of 5000 m
点击查看 >>
Author：
Jiamin Chai, Shiying Liu, Xuan Tian, Jianan Wang, Jigang Wen, Chengli Xu
IF：
5.2000
Publish_to：
LIFE SCIENCES
PMID：
39332487
The Wu-Shi-Cha formula protects against ulcerative colitis by orchestrating immunity and microbiota homeostasis
点击查看 >>
Author：
Wei Yu, Zizheng Jiang, Zhiqiang Zhang, Lu Jiang, Chen Liu, Chang Lu, Zhenghao Liang, Guoliang Wang, Jing Yan
IF：
5.1950
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
36572328
KRT6A expedites bladder cancer progression, regulated by miR-31-5p
点击查看 >>
Author：
Yuan Chen, Shiben Ji, Jianxin Ying, Yongchang Sun, Jun Liu, Guohong Yin
IF：
5.1730
Publish_to：
CELL CYCLE
PMID：
35311447
Mesenchymal stem cell-derived extracellular vesicles alleviate cervical cancer by delivering microRNA-331-3p to reduce LIM zinc finger domain containing 2 methylation in tumor cells
点击查看 >>
Author：
Yang Shanshan, Wang Le, Gu Lina, Wang Zhao, Wang Yuan, Wang Jianan, Zhang Yunyan
IF：
5.1210
Publish_to：
HUMAN MOLECULAR GENETICS
PMID：
35708510
Electroacupuncture Promotes Nerve Regeneration and Functional Recovery Through Regulating lncRNA GAS5 Targeting miR-21 After Sciatic Nerve Injury
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Author：
Tian Ming-yue, Yang Yi-duo, Qin Wan-ting, Liu Bao-nian, Mou Fang-fang, Zhu Jing, Guo Hai-dong, Shao Shui-jin
IF：
5.1000
Publish_to：
MOLECULAR NEUROBIOLOGY
PMID：
37672149
Hypericin Inhibit Alpha-Coronavirus Replication by Targeting 3CL Protease
点击查看 >>
Author：
Yue Zhang, Huijie Chen, Mengmeng Zou, Rick Oerlemans, Changhao Shao, Yudong Ren, Ruili Zhang, Xiaodan Huang, Guangxing Li, Yingying Cong
IF：
5.0480
Publish_to：
Viruses-Basel
PMID：
34578406
DJ-1 modulates Nrf2-mediated MRP1 expression by activating Wnt3a/β-catenin signalling in A549 cells exposed to cigarette smoke extract and LPS
点击查看 >>
Author：
Jian Zhou, Chuanzong Qi, Xin Fang, Zihao Wang, Shuyi Zhang, Dalang Li, Jue Song
IF：
5.0370
Publish_to：
LIFE SCIENCES
PMID：
33476627
TSPAN4 is a prognostic and immune target in Glioblastoma multiforme
点击查看 >>
Author：
Yue Zheng, Yuheng Lang, Bingcai Qi, Yuchao Wang, Wenqing Gao, Tong Li
IF：
5.0000
Publish_to：
Frontiers in Molecular Biosciences
PMID：
36685274
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway
点击查看 >>
Author：
Liang Wen, Qing-Hui Yang, Xiao-Lei Ma, Ting Li, Sa Xiao, Chao-Feng Sun
IF：
4.9320
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
34330059
Baicalin Inhibits FIPV Infection In Vitro by Modulating the PI3K-AKT Pathway and Apoptosis Pathway
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Author：
Zhongda Cao, Nannan Ma, Maoyang Shan, Shiyan Wang, Jige Du, Jia Cheng, Panpan Sun, Na Sun, Lin Jin, Kuohai Fan, Wei Yin, Hongquan Li, Chunsheng Yin, Yaogui Sun
IF：
4.9000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
39337417
PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression
点击查看 >>
Author：
Zhouji Ma, Ran Mo, Ping Yang, Youjun Ding, Hao Zhang, Zheng Dong, Yutong Chen, Qian Tan
IF：
4.8000
Publish_to：
FASEB JOURNAL
PMID：
37737961
Identification of a biomarker and immune infiltration in perivascular adipose tissue of abdominal aortic aneurysm
点击查看 >>
Author：
Wang Xuming, He Bin, Deng Yisen, Liu Jingwen, Zhang Zhaohua, Sun Weiliang, Gao Yanxiang, Liu Xiaopeng, Zhen Yanan, Ye Zhidong, Liu Peng, Wen Jianyan
IF：
4.7550
Publish_to：
Frontiers in Physiology
PMID：
36187757
Hsa_circ_0042823 accelerates cancer progression via miR-877-5p/FOXM1 axis in laryngeal squamous cell carcinoma
点击查看 >>
Author：
Tianyi Wu, Yanan Sun, Zhanwei Sun, Shichao Li, Weiwei Wang, Boyu Yu, Guangke Wang
IF：
4.7090
Publish_to：
ANNALS OF MEDICINE
PMID：
34124974
The GluN1/GluN2B NMDA receptor and metabotropic glutamate receptor 1 negative allosteric modulator has enhanced neuroprotection in a rat subarachnoid hemorrhage model
点击查看 >>
Author：
Zongyong Zhang a,1 , Junke Liu b,1 , Cundong Fan a
IF：
4.7000
Publish_to：
Experimental Neurology
PMID：
29258835
Cysteine protease inhibitor 1 promotes metastasis by mediating an oxidative phosphorylation/MEK/ERK axis in esophageal squamous carcinoma cancer
点击查看 >>
Author：
Zhang Liangming, Chen Xiongfeng, Wang Jianwei, Chen Meihong, Chen Juan, Zhuang Wanzhen, Xia Yu, Huang Zhixin, Zheng Yue, Huang Yi
IF：
4.6000
Publish_to：
Scientific Reports
PMID：
38424293
Long non-coding DANCR targets miR-185-5p to upregulate LIM and SH3 protein 1 promoting prostate cancer via the FAK/PI3K/AKT/GSK3β/snail pathway
点击查看 >>
Author：
Wendong Sun, Shulu Zu, Guangfeng Shao, Wenzhen Wang, Fangxin Gong
IF：
4.5650
Publish_to：
JOURNAL OF GENE MEDICINE
PMID：
33885171
Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats
点击查看 >>
Author：
Liu Xin, Tang Jing, Zhang Runan, Zhan Siyuan, Zhong Tao, Guo Jiazhong, Wang Yan, Cao Jiaxue, Li Li, Zhang Hongping, Wang Linjie
IF：
4.5470
Publish_to：
BMC GENOMICS
PMID：
35864448
Improvement of polydopamine-loaded salidroside on osseointegration of titanium implants
点击查看 >>
Author：
Yi Qingqing, Liang Pengchen, Liang Dongyu, Cao Liou, Sha Shuang, Jiang Xinquan, Chang Qing
IF：
4.5460
Publish_to：
Chinese Medicine
PMID：
35189918
Long non-coding RNA LIFR-AS1 suppressed the proliferation, angiogenesis, migration and invasion of papillary thyroid cancer cells via the miR-31-5p/SIDT2 axis
点击查看 >>
Author：
Dan Yi, Dongxin Zhang, Jie He
IF：
4.5340
Publish_to：
CELL CYCLE
PMID：
34781815
Porous gelatin microspheres implanted with adipose mesenchymal stromal cells promote angiogenesis via protein kinase B/endothelial nitric oxide synthase signaling pathway in bladder reconstruction
点击查看 >>
Author：
Jun Zhao, Tianli Yang, Liuhua Zhou, Jingyu Liu, Liang Mao, Ruipeng Jia, Feng Zhao
IF：
4.5000
Publish_to：
CYTOTHERAPY
PMID：
37804283
CircSERPINA3 promoted cell proliferation, migration, and invasion of laryngeal squamous cell carcinoma by targeting miR-885-5p
点击查看 >>
Author：
Qiushi Xu, Bing Yu, Wenjing Chen, Wenlong Li, Yuanhao Sun, Yanchun Fang
IF：
4.4730
Publish_to：
CELL BIOLOGY INTERNATIONAL
PMID：
35971749
CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling
点击查看 >>
Author：
Xiaolei Feng, Jue Jiang, Lei Sun, Qi Zhou
IF：
4.4600
Publish_to：
TOXICOLOGY AND APPLIED PHARMACOLOGY
PMID：
35219640
Expression of ATP-Binding Cassette Transporter A1 (ABCA1) in Eyelid Tissues and Meibomian Gland Epithelial Cells
点击查看 >>
Author：
Fang Zheng, Jingjing Su, Jiaoman Wang, Qing Zhan, Mei Su, Sicheng Ding, Wei Li, Ying-Ting Zhu, Ping Guo
IF：
4.4000
Publish_to：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
PMID：
38502139
Fraxetin exerts anticancer effect in glioma by suppressing MiR-21-3p
点击查看 >>
Author：
Hanxun Yao, Xiaobin Li, Xuyan Pan, Jie Xu, Shufa Zhao, Zhongzhou Su, Sheng Qiu
IF：
4.3600
Publish_to：
DRUG DEVELOPMENT RESEARCH
PMID：
34523750
Baicalin Alleviates Contrast-Induced Acute Kidney Injury Through ROS/NLRP3/Caspase-1/GSDMD Pathway-Mediated Proptosis in vitro
点击查看 >>
Author：
Yanyan Li, Junda Wang, Dan Huang, Chao Yu
IF：
4.3190
Publish_to：
Drug Design Development and Therapy
PMID：
36196145
DNA N6-methyladenine involvement and regulation of hepatocellular carcinoma development
点击查看 >>
Author：
Qu Lin, Jun-wei Chen, Hao Yin, Ming-an Li, Chu-ren Zhou, Tao-fang Hao, Tao Pan, Chun Wu, Zheng-ran Li, Duo Zhu, Hao-fan Wang, Ming-sheng Huang
IF：
4.3100
Publish_to：
GENOMICS
PMID：
35032618
Oxidized Low-Density Lipoprotein Induces Apoptosis in Cultured Neonatal Rat Cardiomyocytes by Modulating the TLR4/NF-κB Pathway
点击查看 >>
Author：
Xiantao Wang, Yuhan Sun, Huafeng Yang, Yuanxi Lu ,
IF：
4.2590
Publish_to：
Scientific Reports 6, Article number: 27866 (2016)
PMID：
27279424
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis
点击查看 >>
Author：
Qiuli Wang, Dong Liang, Peng Shen, Yang Yu, Yuan Yan, Wei You
IF：
4.2430
Publish_to：
Translational Oncology
PMID：
34023560
Protective effects of recombinant lactoferrin with different iron saturations on enteritis injury in young mice
点击查看 >>
Author：
L.L. Fan, Q.Q. Yao, H.M. Wu, F. Wen, J.Q. Wang, H.Y. Li, N. Zheng
IF：
4.2250
Publish_to：
JOURNAL OF DAIRY SCIENCE
PMID：
35379462
Zearalenone promotes apoptosis of mouse Leydig cells by targeting phosphatase and tensin homolog and thus inhibiting the PI3K/AKT signal pathway
点击查看 >>
Author：
Chen
Jia, Wang Mingyang, Wang Hanli, Long Miao
IF：
4.2230
Publish_to：
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
PMID：
34264493
Fucoxanthin Inhibits the Proliferation and Metastasis of Human Pharyngeal Squamous Cell Carcinoma by Regulating the PI3K/Akt/mTOR Signaling Pathway
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Author：
Hao-Fei Du, Jia-Min Jiang, Si-Han Wu, Yan-Fang Shi, Hai-Tian Liu, Zheng-Hao Hua, Cai-Sheng Wang, Guo-Ying Qian, Hao-Miao Ding
IF：
4.2000
Publish_to：
MOLECULES
PMID：
39125009
Ephedrae Herba polysaccharides inhibit the inflammation of ovalbumin induced asthma by regulating Th1/Th2 and Th17/Treg cell immune imbalance
点击查看 >>
Author：
Beibei Zhang, Mengnan Zeng, Qinqin Zhang, Ru Wang, Jufang Jia, Bing Cao, Meng Liu, Pengli Guo, Yuhan Zhang, Xiaoke Zheng, Weisheng Feng
IF：
4.1740
Publish_to：
MOLECULAR IMMUNOLOGY
PMID：
36215828
Ravoxertinib Improves Long-Term Neurologic Deficits after Experimental Subarachnoid Hemorrhage through Early Inhibition of Erk1/2
点击查看 >>
Author：
Ming-feng Yang, Sheng-yao Sun, Hai-guang Lv, Wei-qi Wang, Han-xia Li, Jing-yi Sun, Zong-yong Zhang
IF：
4.1320
Publish_to：
ACS Omega
PMID：
37305289
PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis
点击查看 >>
Author：
Xiaoxue Meng, Lu Zhang, Bing Han, Zheng Zhang
IF：
4.1190
Publish_to：
ENVIRONMENTAL TOXICOLOGY
PMID：
34351043
Distribution and response strategies of non-specific cytotoxic cell receptor protein 1 in large yellow croaker
点击查看 >>
Author：
Yuxin Yao, Qi Li, Qingpi Yan
IF：
4.1000
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
38936521
MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection
点击查看 >>
Author：
Xie Fujie, Zhang Yajun, Li Juanfeng, Sun Lulu, Zhang Longxian, Qi Meng, Zhang Sumei, Jian Fuchun, Li Xiaoying, Li Junqiang, Ning Changsheng, Wang Rongjun
IF：
4.0470
Publish_to：
Parasites & Vectors
PMID：
35974384
Circadian miR-218-5p targets gene CA2 to regulate uterine carbonic anhydrase activity during egg shell calcification
点击查看 >>
Author：
Xiaxia Du, Zhifu Cui, Zifan Ning, Xun Deng, Felix Kwame Amevor, Gang Shu, Xiaoqi Wang, Zhichao Zhang, Yaofu Tian, Qing Zhu, Yan Wang, Diyan Li, Yao Zhang, Xiaoling Zhao
IF：
4.0140
Publish_to：
POULTRY SCIENCE
PMID：
36167021
Inhibitory activity of acteoside in melanoma via regulation of the ERβ-Ras/Raf1-STAT3 pathway
点击查看 >>
Author：
Yuanyuan Wu, Mengnan Zeng, Ruiqi Xu, Beibei Zhang, Shengchao Wang, Benke Li, Yuxuan Kan, Bing Cao, Xiaoke Zheng, Weisheng Feng
IF：
4.0130
Publish_to：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
PMID：
34174222
Ginsenoside Rg1 attenuates the inflammation and oxidative stress induced by diabetic nephropathy through regulating the PI3K/AKT/FOXO3 pathway
点击查看 >>
Author：
Hui Liu, Wenli Chen, Ping Lu, Yifei Ma, Xinjun Liang, Yanyan Liu
IF：
3.9320
Publish_to：
Annals of Translational Medicine
PMID：
35071483
Methylation gene KCNC1 is associated with overall survival in patients with seminoma
点击查看 >>
Author：
Saipeng Chen, Longfei Xiao, Huahong Peng, Zhen Wang, Jianbing Xie
IF：
3.9060
Publish_to：
ONCOLOGY REPORTS
PMID：
34105734
TET1-mediated microRNA-188-5p promoter hydroxymethylation regulates PTEN/PI3K/AKT signaling pathway in acute myeloid leukemia cells
点击查看 >>
Author：
Nadan Lu, Xiaoyi Wang, Weilin Wang, Miaomiao Tang, Jiao Chen, Hongliang You, Dao Wang
IF：
3.9000
Publish_to：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
PMID：
36682704
Hepatoprotective effect of protocatechuic acid against type 2 diabetes-induced liver injury
点击查看 >>
Author：
Kaixia Xu, Guang Lu, Qianjin Feng, Shuangchao Chen, Yonghui Wang
IF：
3.8890
Publish_to：
PHARMACEUTICAL BIOLOGY
PMID：
37129023
In vitro and in vivo efficacy of thiacloprid against Echinococcus multilocularis
点击查看 >>
Author：
Liu Chuanchuan, Fan Haining, Ma Jie, Ma Lan, Ge Ri-li
IF：
3.8760
Publish_to：
Parasites & Vectors
PMID：
34488852
Down-regulated microRNA-199a-3p enhances osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Kdm3a in ovariectomized rats
点击查看 >>
Author：
Wu Jian-Cheng, Sun Jie, Xu Jia-Cheng, Zhou Zhen-Yu, Zhang Ya-Feng
IF：
3.8570
Publish_to：
BIOCHEMICAL JOURNAL
PMID：
33410908
Apoptotic mechanism of development inhibition in zebrafish induced by esketamine
点击查看 >>
Author：
Wenjuan Yuan, Yinggang Xiao, Yang Zhang, Kuilin Xiang, Tianfeng Huang, Mohamed Diaby, Ju Gao
IF：
3.8000
Publish_to：
TOXICOLOGY AND APPLIED PHARMACOLOGY
PMID：
38103741
The role of Wnt/β-catenin pathway for skin-derived precursors differentiating into corneal endothelial cell-like cells
点击查看 >>
Author：
Lin Shen, Lijie Pan, Chengqun Ju, Xinyi Wu
IF：
3.7700
Publish_to：
EXPERIMENTAL EYE RESEARCH
PMID：
35219695
Epigallocatechin-3-gallate Alleviates Vanadium-Induced Reduction of Antioxidant Capacity via Keap1-Nrf2-sMaf Pathway in the Liver, Kidney, and Ovary of Laying Hens
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Author：
Ma Yan, Shi Yizhen, Wu Qiujue, Ma Wenfeng
IF：
3.7380
Publish_to：
BIOLOGICAL TRACE ELEMENT RESEARCH
PMID：
33405082
β-Sitosterol inhibits ovalbumin-induced asthma-related inflammation by regulating dendritic cells
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Author：
Ru Wang, Mengnan Zeng, Beibei Zhang, Qinqin Zhang, Jufang Jia, Bing Cao, Meng Liu, Pengli Guo, Yuhan Zhang, Xiaoke Zheng, Weisheng Feng
IF：
3.7120
Publish_to：
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
PMID：
35850599
Inhibitory effect and mechanism of Lactobacillus crispatus on cervical precancerous cells Ect1/E6E7 and screening of early warning factors
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Author：
Wan B., Wei L. J., Tan T. M., Qin L., Wang H.
IF：
3.7000
Publish_to：
Infectious Agents and Cancer
PMID：
36726132
Sevoflurane attenuates hepatic ischemia reperfusion injury by the miR-122/Nrf2 pathway
点击查看 >>
Author：
Kai Zhang, Xia Xu, Lihong Hu
IF：
3.6160
Publish_to：
Annals of Translational Medicine
PMID：
35433991
Morphine induces HADHA succinylation, while HADHA desuccinylation alleviates morphine tolerance by influencing autophagy
点击查看 >>
Author：
Huang Yuanxin, Lu Sihui, Chen Yu, Feng Yuanyu, Lu Wei
IF：
3.6000
Publish_to：
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
PMID：
37688624
CD5L induces inflammation and survival in RA-FLS through ERK1/2 MAPK pathway
点击查看 >>
Author：
Huiqing Yang, Yan Luo, Xiaofei Lai
IF：
3.5000
Publish_to：
AUTOIMMUNITY
PMID：
38425093
The Key Genes Underlying Pathophysiology Association between Plaque Instability and Progression of Myocardial Infarction
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Author：
Yue Zheng, Yijie Gong, Yuheng Lang, Zhenchang Qi, Xiaomin Hu, Tong Li
IF：
3.4340
Publish_to：
DISEASE MARKERS
PMID：
34925642
Differential Abundance of Brain Mitochondrial Proteins in Yak and Cattle: A Proteomics-Based Study
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Author：
Ma Xiaoming, Zhang Qiang, La Yongfu, Fu Donghai, Jiang Hiu, Bao Pengjia, Wu Xiaoyun, Chu Min, Guo Xian, Yan Ping, Liang Chunnian
IF：
3.4120
Publish_to：
Frontiers in Veterinary Science
PMID：
34532350
Alkaloids from Corydalis saxicola and their antiproliferative activity against cancer cells
点击查看 >>
Author：
Li Luo, Jia-Zi Luo, Xi-Xi Song, Cai-Yi Wang, De-Ming Tang, Wen-Tao Sun, Cai-Wen Fan, Mei-Shan Li, Heng-Shan Wang
IF：
3.4000
Publish_to：
FITOTERAPIA
PMID：
38159614
miR-182 mediated the inhibitory effects of NF-κB on the GPR39/CREB/ BDNF pathway in the hippocampus of mice with depressive-like behaviors
点击查看 >>
Author：
Yuxiao Tang（第一作者）
IF：
3.3000
Publish_to：
Behavioural Brain Research
PMID：
34743948
Huaier Inhibits Proliferation, Migration, and Invasion of Cutaneous Squamous Cell Carcinoma Cells by Inhibiting the Methylation Levels of CDKN2A and TP53
点击查看 >>
Author：
Liang Wang, Lei Xu, Yu Wang
IF：
3.2790
Publish_to：
INTEGRATIVE CANCER THERAPIES
PMID：
34291682
Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway
点击查看 >>
Author：
Shaojun Nong, Zhongqing Wei, Zhiwei Wang, Limin Ma, Yangbo Guan, Jian Ni
IF：
3.2720
Publish_to：
STEM CELLS AND DEVELOPMENT
PMID：
34289746
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway
点击查看 >>
Author：
Jian Yang, Yong Hu, Lu Wang, Xiangran Sun, Ling Yu, Weichun Guo
IF：
3.2690
Publish_to：
Bioengineered
PMID：
34781817
Comparative transcriptomic analysis of porcine epidemic diarrhea virus epidemic and classical strains in IPEC-J2 cells
点击查看 >>
Author：
Yue Zhang, Huijie Chen, Jia Yu, Rui Feng, Zhao Chen, Xiaolin Zhang, Yudong Ren, Guijun Yang, Xiaodan Huang, Guangxing Li
IF：
3.2460
Publish_to：
VETERINARY MICROBIOLOGY
PMID：
35987184
Comparative transcriptome analysis of leaves during early stages of chilling stress in two different chilling-tolerant brown-fiber cotton cultivars
点击查看 >>
Author：
Shouwu Tang, Yajie Xian, Fei Wang, Cheng Luo, Wu Song, Shuangquan Xie, Xifeng Chen, Aiping Cao, Hongbin Li, Haifeng Liu
IF：
3.2400
Publish_to：
PLoS One
PMID：
33561168
A Proteomic Study of the Effect of N-acetylcysteine on the Regulation of Early Pregnancy in Goats
点击查看 >>
Author：
Peifang Yang, Xiang Chen, Xingzhou Tian, Zhinan Zhou, Yan Zhang, Wen Tang, Kaibin Fu, Jiafu Zhao, Yong Ruan
IF：
3.2310
Publish_to：
Animals
PMID：
36139298
Epimedium sagittatum Maxim ameliorates adriamycin-induced nephropathy by restraining inflammation and apoptosis via the PI3K/AKT signaling pathway
点击查看 >>
Author：
Ru Wang, Mengnan Zeng, Beibei Zhang, Qinqin Zhang, Shuangshuang Xie, Yingbo Hu, Ruyi Fan, Mengya Wang, Xiao Yu, Yuhan Zhang, Xiaoke Zheng, Weisheng Feng
IF：
3.2000
Publish_to：
Immunity Inflammation and Disease
PMID：
37382268
Palmitoylethanolamide ameliorates neuroinflammation via modulating PPAR-α to promote the functional outcome after intracerebral hemorrhage
点击查看 >>
Author：
Guoyang Zhou, Xiongjie Fu, Liang Wang, Yang Cao, JianFeng Zhuang, Junwen Hu, Yin Li, Chaoran Xu, Shiqi Gao, Anwen Shao, Lin Wang
IF：
3.1970
Publish_to：
NEUROSCIENCE LETTERS
PMID：
35469820
Carboxymethylated pachyman induces ferroptosis in ovarian cancer by suppressing NRF1/HO‑1 signaling
点击查看 >>
Author：
Tiantian Jing, Yanli Guo, Yanqiu Wei
IF：
3.1110
Publish_to：
Oncology Letters
PMID：
35399331
Upregulation of LPGAT1 Enhances Lung Adenocarcinoma Proliferation
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Author：
Huiyuan Gong, Chao Ma, Xiaojun Li, Xueying Zhang, Linxiang Zhang, Pengfei Chen, Wei Wang, Yannan Hu, Ting Huang, Nan Wu, Xiaojing Wang
IF：
3.1000
Publish_to：
Frontiers in Bioscience-Landmark
PMID：
37258473
Islet MC4R Regulates PC1/3 to Improve Insulin Secretion in T2DM Mice via the cAMP and β-arrestin-1 Pathways
点击查看 >>
Author：
Ni Zaizhong, Wang Yanan, Shi Cong, Zhang Xinping, Gong Hao, Dong Yuwei
IF：
3.0940
Publish_to：
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
PMID：
35900711
Transcriptomic profile of human erythroleukemia cells in response to Sargassum fusiforme polysaccharide and its structure analysis
点击查看 >>
Author：
Hao-Miao DING, Rui-Jie FU, Ce XIE, Cai-Sheng WANG, Guo-Ying QIAN
IF：
3.0000
Publish_to：
Chinese Journal of Natural Medicines
PMID：
34688468
miR-155-5p upregulation ameliorates myocardial insulin resistance via mTOR signaling in chronic alcohol drinking rats
点击查看 >>
Author：
Zhaoping Li, Zhenzhen Hu, Yan Meng, Hongzhao Xu, Yali Wei, Deqiang Shen, Hao Bai, Huacai Yuan, Liyong Chen
IF：
2.9840
Publish_to：
PeerJ
PMID：
33868799
Exosomal miR‑130a‑3p promotes the progression of differentiated thyroid cancer by targeting insulin‑like growth factor 1
点击查看 >>
Author：
Guang Yin, Wencheng Kong, Sixin Zheng, Yuqiang Shan, Jian Zhang, Rongchao Ying, Hao Wu
IF：
2.9670
Publish_to：
Oncology Letters
PMID：
33732359
miR-10a-5p inhibits chicken granulosa cells proliferation and Progesterone(P4) synthesis by targeting MAPRE1 to suppress CDK2
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Author：
Dongmei Li, Xinyan Li, Haorong He, Yao Zhang, Hua He, Congjiao Sun, Xinyi Zhang, Xunzi Wang, Zhaoyi Kan, Yang Su, Shunshun Han, Lu Xia, Bo Tan, Mengen Ma, Qing Zhu, Huadong Yin, Can Cui
IF：
2.9230
Publish_to：
THERIOGENOLOGY
PMID：
36084389
MiR-132-3p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting TGF-β1/Smad2/3 signaling pathway
点击查看 >>
Author：
Yangyang Yin, Yuqi Yang, Yongqiang Zhang, Yu Shang, Qian Li, Jing Yuan
IF：
2.9000
Publish_to：
PLoS One
PMID：
38603722
Cryptosporidium parvum downregulates miR-181d in HCT-8 cells via the p50-dependent TLRs/NF-κB pathway
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Author：
Ruiying Feng, Ziwen Niu, Xiaotian Zhang, Wenyan Hou, Yingying Zhang, Fuchun Jian, Changshen Ning, Longxian Zhang, Sumei Zhang, Rongjun Wang
IF：
2.8210
Publish_to：
VETERINARY PARASITOLOGY
PMID：
35462275
Alginate oligosaccharide alleviates senile osteoporosis via the RANKL–RANK pathway in D-galactose-induced C57BL/6J mice
点击查看 >>
Author：
Shan Wang, Wenjing Feng, Jianya Liu, Xufu Wang, Lina Zhong, Chengxiu Lv, Meiping Feng, Nina An, Yongjun Mao
IF：
2.8170
Publish_to：
Chemical Biology & Drug Design
PMID：
34145772
Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit gastric adenocarcinoma malignant characteristics by targeting miR-223–3p
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Author：
Li Liu, Xuefeng Li, Lingli Song, Yuhan Yang, Binxian Li
IF：
2.8000
Publish_to：
PATHOLOGY RESEARCH AND PRACTICE
PMID：
38678850
High level of FHL2 exacerbates the outcome of non-small cell lung cancer (NSCLC) patients and the malignant phenotype in NSCLC cells
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Author：
Na Li, Ling Xu, Ji Zhang, Yongyu Liu
IF：
2.7930
Publish_to：
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
PMID：
35366027
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway
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Author：
Mao Yongzhong, Jiang Ling
IF：
2.7810
Publish_to：
Journal of Physiological Sciences
PMID：
34525946
Effect of Actin Alpha Cardiac Muscle 1 on the Proliferation and Differentiation of Bovine Myoblasts and Preadipocytes
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Author：
Anqi Li, Xiaotong Su, Yuan Tian, Guibing Song, Linsen Zan, Hongbao Wang
IF：
2.7520
Publish_to：
Animals
PMID：
34944244
Sevoflurane preconditioning prevents acute renal injury caused by ischemia‑reperfusion in mice via activation of the Nrf2 signaling pathway
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Author：
Wen-Xi Wang, Zhen-Ru Zhao, Ying Bai, Ya-Xing Li, Xiao-Ning Gao, Sen Zhang, Yan-Bin Sun
IF：
2.7510
Publish_to：
Experimental and Therapeutic Medicine
PMID：
35340877
Molecular characterization, expression patterns and cellular localization of BCAS2 gene in male Hezuo pig
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Author：
Yuran Tang, Bo Zhang, Haixia Shi, Zunqiang Yan, Pengfei Wang, Qiaoli Yang, Xiaoyu Huang, Shuangbao Gun
IF：
2.7000
Publish_to：
PeerJ
PMID：
37901468
CXCR4 promotes gefitinib resistance of Huh7 cells by activating the c-Met signaling pathway
点击查看 >>
Author：
Dali Zhao, Zhiqiang Yang, Chen Chen, Zhipeng Zhang, Yangsheng Yu, Zhituo Li
IF：
2.6930
Publish_to：
FEBS Open Bio
PMID：
34555268
Abdominal paracentesis drainage attenuates intestinal mucosal barrier damage through macrophage polarization in severe acute pancreatitis
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Author：
Xiaohui Yuan, Chen Luo, Jun Wu, Wei Li, Xin Guo, Shuai Li, Bing Wang, Hongyu Sun, Lijun Tang
IF：
2.6910
Publish_to：
EXPERIMENTAL BIOLOGY AND MEDICINE
PMID：
34053233
Cryptotanshinone Suppressed Postmenopausal Osteoporosis by Preventing RANKL-Mediated Osteoclastogenesis against Kidney Injury
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Author：
Wenjiu Yang, Jing Han, Shuo Gong, Jun Zhao, Tengbo Yu, Jinfeng Ma
IF：
2.6500
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
35132325
CircSCMH1 Accelerates Sorafenib Resistance in Hepatocellular Carcinoma by Regulating HN1 Expression via miR-485-5p
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Author：
Li Meixiang, Pang Xionghao, Xu Haixia, Xiao Liang
IF：
2.6000
Publish_to：
MOLECULAR BIOTECHNOLOGY
PMID：
38372878
Resveratrol ameliorates thoracic blast exposure-induced inflammation, endoplasmic reticulum stress and apoptosis in the brain through the Nrf2/Keap1 and NF-κB signaling pathway
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Author：
Peifang Cong, Teng Wang, Changci Tong, Ying Liu, Lin Shi, Shun Mao, Xiuyun Shi, Hongxu Jin, Yunen Liu, Mingxiao Hou
IF：
2.5860
Publish_to：
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
PMID：
34454721
The Role of HMGB1 in Invasive Candida albicans Infection
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Author：
Wang JiaoJiao, Wu ChuanXin, Wang YunYing, Chen ChongXiang, Cheng Jing, Rao XiaoLong, Sun Hang
IF：
2.5740
Publish_to：
MYCOPATHOLOGIA
PMID：
34608551
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus
点击查看 >>
Author：
Guohao Yuan, Ling Xiao, Yinping Xie, Lujia Si, Hong Xu, Wenqian Xu, Gaohua Wang
IF：
2.5000
Publish_to：
NEUROSCIENCE LETTERS
PMID：
36623760
Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy
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Author：
Hongxi Wu, Guodong Li, Weiwei Chen, Wenbin Luo, Zhongyi Yang, Zhipeng You, Yuling Zou
IF：
2.4790
Publish_to：
ACTA HISTOCHEMICA
PMID：
34959219
UTMD-mediated delivery of miR-21-5p inhibitor suppresses the development of lung cancer
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Author：
Xiaoyu Zhou, Haitao Liu, Yingying Pang, Muqun Wang, Shengming Liu
IF：
2.4660
Publish_to：
TISSUE & CELL
PMID：
34979378
Effects of sevoflurane general anesthesia during early pregnancy on AIM2 expression in the hippocampus and parietal cortex of Sprague‑Dawley offspring rats
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Author：
Yulin Zhu, Chao Lv, Jingying Liu, Shujun Shang, Wei Jing
IF：
2.4470
Publish_to：
Experimental and Therapeutic Medicine
PMID：
33767764
Protective effect of resveratrol on mitochondrial biogenesis during hyperoxia-induced brain injury in neonatal pups
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Author：
Yang Menghan, Shen Yunchuan, Zhao Shuai, Zhang Rong, Dong Wenbin, Lei Xiaoping
IF：
2.4000
Publish_to：
BMC NEUROSCIENCE
PMID：
37098490
Moniezia benedeni drives the SNAP-25 expression of the enteric nerves in sheep's small intestine
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Author：
Huang Zhen, Yao Wanling, He Wanhong, Pan Jing, Chai Wenzhu, Wang Baoshan, Jia Zhitao, Fan Xiping, Wang Wenhui, Zhang Wangdong
IF：
2.3000
Publish_to：
BMC Veterinary Research
PMID：
38956647
Hsa_circ_0000345 inhibits cell proliferation, migration and invasion of nasopharyngeal carcinoma cells via miR-513a-3p/PTEN axis
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Author：
Jiang Chang, Li Hongyan, Liu Fei, Shi Linggai, Liu Jun, Li Yujie
IF：
2.2570
Publish_to：
Journal of Physiological Sciences
PMID：
35545766
Circ_0085495 knockdown reduces adriamycin resistance in breast cancer through miR-873-5p/integrin β1 axis
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Author：
Xie Hua, Zheng Rongsheng
IF：
2.2480
Publish_to：
ANTI-CANCER DRUGS
PMID：
34387598
ALKBH5 modulates m6A modification to enhance acute myeloid leukemia resistance to adriamycin
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Author：
Yonghua Liu, Jinhong Jiang, Yuxiao Zeng, Yu Jiang
IF：
2.2000
Publish_to：
Biomolecules and Biomedicine
PMID：
39465506
Platelet miR-107 Participates in Clopidogrel Resistance after PCI Treatment by Regulating P2Y12
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Author：
Zhang Qi, Zhu Fan, Luo Yuyin, Liao Jun, Cao Jiancheng, Xue Tao
IF：
2.1950
Publish_to：
ACTA HAEMATOLOGICA
PMID：
34474410
Seaweed polysaccharide mitigates intestinal barrier dysfunction induced by enterotoxigenic Escherichia coli through NF-κB pathway suppression in porcine intestinal epithelial cells
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Author：
Xiaobo Guo, Jun Chen, Jin Yang, Qin He, Bowen Luo, Yafei Lu, Tiande Zou, Zirui Wang, Jinming You
IF：
2.1300
Publish_to：
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
PMID：
33817860
Screening and identification of effective components from modified Taohong Siwu decoction for protecting H9c2 cells from damage
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Author：
Wang Ya-chao, Wang Huan, Shao Chang-le, Li Xiu-ya, Cui Ji, Guo Hai-dong
IF：
2.1000
Publish_to：
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
PMID：
37294373
Upregulation of glutamate transporter 1 by mTOR/Akt pathway in astrocyte culture during oxygen–glucose deprivation and reoxygenation
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Author：
Li Mi, Yu Jingmei, Deng Huan, Xie Shansha, Li Qiuling, Zhao Yuping, Yin Shubin, Ji Yi-Fei
IF：
2.0640
Publish_to：
EXPERIMENTAL BRAIN RESEARCH
PMID：
36436003
Selinexor assists vorinostat in inhibiting HDAC activity via promoting the accumulation of maspin in the nucleus of oral tongue squamous cell carcinoma cells
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Author：
Yuan Fenqian, Yong Jingkang, Liu Xueming, Wang Yifeng
IF：
2.0400
Publish_to：
CYTOTECHNOLOGY
PMID：
36713062
Hsa_circ_0070440 promotes lung adenocarcinoma progression by SLC7A11-mediated-ferroptosis
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Author：
Yong Zhao, Qichen Cui, Jian Shen, Weihong Shen, Yuan Weng
IF：
2.0000
Publish_to：
HISTOLOGY AND HISTOPATHOLOGY
PMID：
36852950
GATA3 promotes the autophagy and activation of hepatic stellate cell in hepatic fibrosis via regulating miR-370/HMGB1 pathway
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Author：
Zhengyuan Xie, Yangyang Li, Peiguang Xiao, Shanmiao Ke
IF：
1.9000
Publish_to：
Gastroenterologia y Hepatologia
PMID：
37207965
Ac-FLTD-CMK inhibits pyroptosis and exerts neuroprotective effect in a mice model of traumatic brain injury
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Author：
Wang Pengfei, Pan Baogen, Tian Jun, Yang Lei, Chen Zeshang, Yang Lijun, Fan Zhenzeng
IF：
1.8370
Publish_to：
NEUROREPORT
PMID：
33470761
Protective mechanisms of Juncus effusus and Carbonized Juncus effusus against d-galactosamine-induced acute liver injury in mice
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Author：
Xiangming Wang, Menghui Zhao, Chengguo Ju, Hui Gao, Wei Wang
IF：
1.7000
Publish_to：
CHEMICAL & PHARMACEUTICAL BULLETIN
PMID：
38325836
miR 199b 5p inhibits triple negative breast cancer cell proliferation, migration and invasion by targeting DDR1
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Author：
Anhao Wu,Yan Chen,Yang Liu,Yafang Lai,Dequan Liu
IF：
1.6640
Publish_to：
Oncology Letters
PMID：
30250555
Increased Expression of MST1 in Patients With Epilepsy and in a Rat Model of Epilepsy
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Author：
Di Xia, Linming Zhang, Rong Mei, Chunhua Wu, Yan Liu, Hongyu Chen, Ling Chen
IF：
1.6000
Publish_to：
SYNAPSE
PMID：
39729046
SFRP1 reduces neutrophil infiltration and inhibits the Wnt/β-catenin pathway to alleviate oral submucous fibrosis
点击查看 >>
Author：
Zhou Rong, Yin Lin, Zhang Xin, Zhu Keke
IF：
1.5000
Publish_to：
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
PMID：
39017751
WTAP-mediated m6A modification on BASP1 mRNA contributes to ferroptosis in AAA
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Author：
Tian Zexiang, Li Wei, Wang Jian, Li Shuzhen
IF：
1.1000
Publish_to：
General Thoracic and Cardiovascular Surgery
PMID：
39969669
Exercise-induced Activation of SIRT1/BDNF/mTORC1 Signaling Pathway: A Novel Mechanism to Reduce Neuroinflammation and Improve Post-stroke Depression
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Author：
Junze Tang, Lina Lu, Jiabo Yuan, Lin Feng
IF：
1.0000
Publish_to：
ACTAS ESPANOLAS DE PSIQUIATRIA
PMID：
40071363
Mechanism of Cistanche deserticola Ma in the Treatment of Myocardial Ischemia-Reperfusion (I/R) Injury Based on Network Pharmacology and In Vitro Experiments
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Author：
Yuan-Jia Yue, Yu Li, Huimin Wang, Zhao Ji, Xing Rong, Lin Jiang
IF：
0.7000
Publish_to：
Pharmacognosy Magazine
PMID：
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细胞裂解后，离心取上清是用12000g离心30min，还是12000rpm？说明书上是写12000g，但我们实验室的离心机达不到要求，有些人是用12000rpm，所以12000rpm可以用吗?2023-12-11 18:15:31
您好，在蛋白提取过程中需离心去除不溶物，常规要求离心力在10000g-14000g即可。您可将自己所用离心机转子半径（R）带入离心力（G）与转速（rpm）换算公式计算您最高转速是否可达到10000g离心力的要求。公式如下：G=1.11×10^(-5)×R×(rpm)^2。
提取组织蛋白，所需的最少组织量是多少?2023-06-13 08:41:39
您好，因样本而异，一般建议按照说明书中的0.1g称取。