Critical Micelle Concentration (CMC): 3-11 mM
2-[(3α,7α,12α-trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid, cholaic acid sodium salt
Sodium taurocholate, the sodium salt of taurocholic acid, is the conjugation product of cholic acid with
taurine and the principal constituent of the bile of carnivorous animals. In vivo, cholesterol is converted to
trihydroxycoprostanote and subsequently to cholyl CoA, which is then conjugated to the amino group of
taurine to form taurocholate.Sodium taurocholate is a known activator of cholesterol esterase.Studies of
various lipases incorporate sodium taurocholate as an activator. Cell culture studies that use taurocholate
have included the colonization by Neisseria meningitidis in cultured human nasopharyngeal mucosae,
permeationof bile salt and bile salt:fatty acid mixed micellar systems in CaCo2 cells, and the infection of
MDBK and HCT-8 cells by the parasite Cryptosporidium parvum.
This product is soluble in water (100 mg/ml), yielding a clear, faint yellow solution.
Store the product at room temperature. It should be reevaluated every two years for suitability in user
Precautions and Disclaimer:
For Laboratory Use Only. Not for drug, household or other uses.