中文
英语
产品简介
| 别名 | DNA转染增强剂 |
| 英文名称 | Polybrene (10mg/ml) |
| 中文名称 | 聚凝胺(10mg/ml) DNA转染增强剂 |
| 储存条件 | -20℃，有效期2年 |
| 运输条件 | 冷冻运输 |
| 规格 | 500ul 5*500ul |
| 单位 | 支 |
Polybrene（聚凝胺，hexadimethrine bromide）是一种多聚阳离子聚合物，常用于哺乳动物细胞的DNA转染实验以增强脂质体的转染效率。Polybrene目前广泛用于逆转录病毒介导的基因转染，慢病毒介导的基因转染，作用机理可能是通过中和细胞表面唾液酸与病毒颗粒之间的静电排斥从而促进吸附作用。Polybrene也是一种有名的抗肝素剂（肝素拮抗剂），常用来生产非特异性凝集的红细胞。另外Polybrene也多用于蛋白测序，因为小剂量的Polybrene在自动测序分析可明显改善多肽的降解现象。PVDF膜加入polybrene还能提高膜的亲和性。
本产品为即用型溶液，粉末用0.9%NaCl配置成10mg/ml的溶液，并用0.22μM滤膜过滤除菌。使用时一般按1:1000-1：2000稀释，依细胞种类不同稀释比例不同，具体查阅相关文献。
注：Polybrene对某些细胞（如末端分化的神经元，DC细胞）毒性较大，初次应用建议先做毒性测试。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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Zhang Ping, Qin Mengting, Wang Yang, Chen Xiaodong, Miao Yinsha, Yuan Meng, Zhou Wen, Li Dandan, Wang Dan, Wang Mengying, Ai Li, Ma Yunfeng, Dong Yanying, Ji Yanhong
IF：
7.6370
Publish_to：
Blood Advances
PMID：
35816360
Macrophage Polarization Modulated by Porcine Circovirus Type 2 Facilitates Bacterial Coinfection
点击查看 >>
Author：
Zhang Wen, Fu Zhendong, Yin Hongyan, Han Qingbing, Fan Wenhui, Wang Fangkun, Shang Yingli
IF：
7.5610
Publish_to：
Frontiers in Immunology
PMID：
34394082
The Recombinant Eg.P29- Mediated miR-126a-5p Promotes the Differentiation of Mouse Naive CD4+ T Cells via DLK1-Mediated Notch1 Signal Pathway
点击查看 >>
Author：
杜先才
IF：
7.5000
Publish_to：
Frontiers in immunology
PMID：
35211114
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity
点击查看 >>
Author：
Zhengjie Kong, Hongyan Yin, Fan Wang, Zhen Liu, Xiaohan Luan, Lei Sun, Wenjun Liu, Yingli Shang
IF：
7.4640
Publish_to：
PLoS Pathogens
PMID：
35584187
LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through the MEK/ERK signaling pathway
点击查看 >>
Author：
Ziye Chen, Lu Chen, Bo Sun, Dongming Liu, Yuchao He, Lisha Qi, Guangtao Li, Zhiqiang Han, Linlin Zhan, Su Zhang, Keyun Zhu, Yi Luo, Liwei Chen, Ning Zhang, Hua Guo
IF：
7.4220
Publish_to：
Molecular Metabolism
PMID：
33823318
A triphosphate tunnel metalloenzyme from pear (PbrTTM1) moonlights as an adenylate cyclase
点击查看 >>
Author：
Gao Enyi, Sun Xiaoya, Thorne Rick Francis, Zhang Xu Dong, Li Jinming, Shao Fengmin, Ma Jianli, Wu Mian
IF：
7.4000
Publish_to：
Journal of Translational Medicine
PMID：
37340421
Inhibition of TRF2 Leads to Ferroptosis,Autophagic Death,and Apoptosis by Causing Telomere Dysfunction
点击查看 >>
Author：
Qiuhui Yang, Ziyang Nie, Yukun Zhu, Mingying Hao, Siqi Liu, Xuelu Ding, Feng Wang, Fei Wang, Xin Geng
IF：
7.3100
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
37113742
Mast cell activation mediates blood–brain barrier impairment and cognitive dysfunction in septic mice in a histamine-dependent pathway
点击查看 >>
Author：
Jianhe Yue, Ying Tan, Renzheng Huan, Jin Guo, Sha Yang, Mei Deng, Yunbiao Xiong, Guoqiang Han, Lin Liu, Jian Liu, Yuan Cheng, Yan Zha, Jiqin Zhang
IF：
7.3000
Publish_to：
Frontiers in Immunology
PMID：
36817492
FGF10 mitigates doxorubicin-induced myocardial toxicity in mice via activation of FGFR2b/PHLDA1/AKT axis
点击查看 >>
Author：
Zhou De-pu, Deng Lian-cheng, Feng Xiao, Xu Hui-jing, Tian Ye, Yang Wei-wei, Zeng Ping-ping, Zou Li-hui, Yan Xi-hua, Zhu Xia-yan, Shu Dan-hua, Guo Qiang, Huang Xiao-ying, Bellusci Saverio, Lou Zhenkun, Li Xiao-kun, Zhang Jin-San
IF：
7.1690
Publish_to：
ACTA PHARMACOLOGICA SINICA
PMID：
37225844
LRRC45 accelerates bladder cancer development and ferroptosis inhibition via stabilizing NRF2 by competitively KEAP1 interaction
点击查看 >>
Author：
Linwei Fan, Dingfan Guo, Chao Zhu, Chenqi Gao, Yu Wang, Fang Yin, Mengwei Liu, Yanyu Zhou, Tiancheng Wei, Xinxin Xiong, Kuai Yu, Aiping Le
IF：
7.1000
Publish_to：
FREE RADICAL BIOLOGY AND MEDICINE
PMID：
39522565
Heat shock protein HSPA13 promotes hepatocellular carcinoma progression by stabilizing TANK
点击查看 >>
Author：
Cen Xuesong, Lu Yuyan, Lu Jing, Luo Changhong, Zhan Ping, Cheng Yizhe, Yang Fan, Xie Chengrong, Yin Zhenyu, Wang Fuqiang
IF：
7.0000
Publish_to：
Cell Death Discovery
PMID：
38062023
STUB1 regulates antiviral RNAi through inducing ubiquitination and degradation of Dicer and AGO2 in mammals
点击查看 >>
Author：
Shumin Zhang, Xuhua Zhang, Yuanyuan Bie, Jing Kong, An Wang, Yang Qiu, Xi Zhou
IF：
6.9470
Publish_to：
VIROLOGICA SINICA
PMID：
35533808
A positive feedback loop of OTUD1 and c-Jun driven by leptin expedites stemness maintenance in ovarian cancer
点击查看 >>
Author：
Wang Jingtao, Yang Fan, Chen Yurou, Xing Yuzhu, Huang Juyuan, Cao Jing, Xiong Jiaqiang, Liu Yanyan, Zhao Qiuyan, Luo Manwen, Xiong Jie, Fan Guanlan, Lyu Qiongying, Li Feng, Zhang Wei
IF：
6.9000
Publish_to：
ONCOGENE
PMID：
40108305
Oncogenic magnesium transporter 1 upregulates programmed death-1-ligand 1 expression and contributes to growth and radioresistance of glioma cells through the ERK/MAPK signaling pathway
点击查看 >>
Author：
Yuanyuan Wu, Hongbing Wang, Dongdong Wei
IF：
6.8320
Publish_to：
Bioengineered
PMID：
35416125
Special AT-rich sequence-binding protein 2 (Satb2) synergizes with Bmp9 and is essential for osteo/odontogenic differentiation of mouse incisor mesenchymal stem cells
点击查看 >>
Author：
Qiuman Chen, Liwen Zheng, Yuxin Zhang, Xia Huang, Feilong Wang, Shuang Li, Zhuohui Yang, Fang Liang, Jing Hu, Yucan Jiang, Yeming Li, Pengfei Zhou, Wenping Luo, Hongmei Zhang
IF：
6.8310
Publish_to：
CELL PROLIFERATION
PMID：
33660290
Circ_0004676 exacerbates triple-negative breast cancer progression through regulation of the miR-377-3p/E2F6/PNO1 axis
点击查看 >>
Author：
Shao Guoli, Fan Xulong, Zhang Pusheng, Liu Xuewen, Huang Lei, Ji Shufeng
IF：
6.8190
Publish_to：
CELL BIOLOGY AND TOXICOLOGY
PMID：
35870038
Systematic Structural Modification of Squaraine Dye for Near-Infrared Window One and Two Multiplexed In Vivo Imaging and Photothermal Therapy
点击查看 >>
Author：
Ruihu Song, Yiyun Dong, Zhuoyi Zhong, Qi Zhao, Yue Hu, Meiling Lei, Peng Lei, Zhaoning Jiang, Kun Qian, Chenchen Shi, Zhong He, Ye Qin, Jing Wang, Hao Chen
IF：
6.8000
Publish_to：
JOURNAL OF MEDICINAL CHEMISTRY
PMID：
38842846
Hepatitis B virus hijacks TSG101 to facilitate egress via multiple vesicle bodies
点击查看 >>
Author：
Yingcheng Zheng, Mengfei Wang, Sitong Li, Yanan Bu, Zaichao Xu, Guoguo Zhu, Chuanjian Wu, Kaitao Zhao, Aixin Li, Quan Chen, Jingjing Wang, Rong Hua, Yan Teng, Li Zhao, Xiaoming Cheng, Yuchen Xia
IF：
6.7000
Publish_to：
PLoS Pathogens
PMID：
37224147
A Functional Variant Rs492554 Associated With Congenital Heart Defects Modulates SESN2 Expression Through POU2F1
点击查看 >>
Author：
Yang Wenke, Li Yi, Bai Jun, You Tao, Yi Kang, Xie Dingxiong, Zhang Xiaowei, Xie Xiaodong
IF：
6.6840
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
34249922
ESP-B4 promotes nasal epithelial cell-derived extracellular vesicles containing miR-146a-5p to modulate Smad3/GATA-3 thus relieving allergic rhinitis: ESP-B4/miR-146a-5p in AR
点击查看 >>
Author：
He Li, Yuming Wang, Xiuli Han
IF：
6.6560
Publish_to：
PHYTOMEDICINE
PMID：
36370637
Nasopharyngeal cancer cell-derived exosomal PD-L1 inhibits CD8+ T-cell activity and promotes immune escape.
点击查看 >>
Author：
Jie Yang, Jierong Chen, Hu Liang, Yahui Yu
IF：
6.5180
Publish_to：
CANCER SCIENCE
PMID：
35598173
Targeting the transcription factor YY1 is synthetic lethal with loss of the histone demethylase KDM5C
点击查看 >>
Author：
ZhengQian , LiPengfei , QiangYulong , FanJiachen , XingYuzhu , ZhangYing , YangFan , LiFeng , XiongJie
IF：
6.5000
Publish_to：
EMBO REPORTS
PMID：
39433896
BCKDK alters the metabolism of non-small cell lung cancer
点击查看 >>
Author：
Yanhui Wang, Jiawei Xiao, Wenna Jiang, Duo Zuo, Xia Wang, Yu Jin, Lu Qiao, Haohua An, Lexin Yang, Daphne W. Dumoulin, Wolfram C. M. Dempke, Sarah A. Best, Li Ren
IF：
6.4980
Publish_to：
Translational Lung Cancer Research
PMID：
35070754
DNA methyltransferase 1 inhibits microRNA-497 and elevates GPRC5A expression to promote chemotherapy resistance and metastasis in breast cancer
点击查看 >>
Author：
Liu Yaobang, Bai Zhengyang, Chai Dahai, Gao Yali, Li Ting, Ma Yinling, Li Jinping
IF：
6.4290
Publish_to：
Cancer Cell International
PMID：
35255904
Therapeutic Potential of Exosomal circRNA Derived from Synovial Mesenchymal Cells via Targeting circEDIL3/miR-485-3p/PIAS3/STAT3/VEGF Functional Module in Rheumatoid Arthritis
点击查看 >>
Author：
Juan Zhang, Yue Zhang, Yeye Ma, Lili Luo, Maolin Chu, Zhiyi Zhang
IF：
6.4000
Publish_to：
International Journal of Nanomedicine
PMID：
34887661
Breast cancer cell-derived extracellular vesicles transfer miR-182-5p and promote breast carcinogenesis via the CMTM7/EGFR/AKT axis
点击查看 >>
Author：
Lu Chong, Zhao Yu, Wang Jing, Shi Wei, Dong Fang, Xin Yue, Zhao Xiangwang, Liu Chunping
IF：
6.3540
Publish_to：
MOLECULAR MEDICINE
PMID：
34294040
Redirecting anti-Vaccinia virus T cell immunity for cancer treatment by AAV-mediated delivery of the VV B8R gene
点击查看 >>
Author：
Dujuan Cao, Qianqian Song, Junqi Li, Louisa S. Chard Dunmall, Yuanyuan Jiang, Bin Qin, Jianyao Wang, Haoran Guo, Zhenguo Cheng, Zhimin Wang, Nicholas R. Lemoine, Shuangshuang Lu, Yaohe Wang
IF：
6.3110
Publish_to：
Molecular Therapy-Oncolytics
PMID：
35615262
YAP/TAZ mediates resistance to KRAS inhibitors through inhibiting proapoptosis and activating the SLC7A5/mTOR axis
点击查看 >>
Author：
Wang Yang, Ming Zhang, Tian-Xing Zhang, Jia-Hui Liu, Man-Wei Hao, Xu Yan, Haicheng Gao, Qun-Ying Lei, Jiuwei Cui, Xin Zhou
IF：
6.3000
Publish_to：
JCI Insight
PMID：
39704172
Chemotherapy-induced executioner caspase activation increases breast cancer malignancy through epigenetic de-repression of CDH12
点击查看 >>
Author：
Wang Yuxing, Wang Ru, Liu Xiaohe, Liu Menghao, Sun Lili, Pan Xiaohua, Hu Huili, Jiang Baichun, Zou Yongxin, Liu Qiao, Gong Yaoqin, Wang Molin, Sun Gongping
IF：
6.2000
Publish_to：
Oncogenesis
PMID：
37355711
Wogonin protects glomerular podocytes by targeting Bcl-2-mediated autophagy and apoptosis in diabetic kidney disease
点击查看 >>
Author：
Liu Xue-qi, Jiang Ling, Li Yuan-yuan, Huang Yue-bo, Hu Xue-ru, Zhu Wei, Wang Xian, Wu Yong-gui, Meng Xiao-ming, Qi Xiang-ming
IF：
6.1500
Publish_to：
ACTA PHARMACOLOGICA SINICA
PMID：
34253875
MYC-mediated silencing of miR-181a-5p promotes pathogenic Th17 responses by modulating AKT3-FOXO3 signaling
点击查看 >>
Author：
Sisi Chen, Binyun Ma, Xue Li, Kailang Zhang, Yankai Wei, Bei Du, Xun Liu, Ruihua Wei, Xiaorong Li, Hong Nian
IF：
6.1070
Publish_to：
iScience
PMID：
36248732
Oncogenic 汕-catenin-driven liver cancer is susceptible to methotrexate-mediated disruption of nucleotide synthesis
点击查看 >>
Author：
Liu Fangming, Wu Yuting, Zhang Baohui, Yang Shuhui, Shang Kezhuo, Li Jie, Zhang Pengju, Deng Weiwei, Chen Linlin, Zheng Liang, Gai Xiaochen, Zhang Hongbing
IF：
6.1000
Publish_to：
CHINESE MEDICAL JOURNAL
PMID：
37612257
METTL16 predicts a favorable outcome and primes antitumor immunity in pancreatic ductal adenocarcinoma
点击查看 >>
Author：
Lu Liting, Zheng Dandan, Qu Junchi, Zhuang Yanyan, Peng Juanfei, Lan Sihua, Zhang Shineng, Huang Fengting
IF：
6.0810
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
36158188
CircUBR5 acts as a ceRNA for miR-1179 to up-regulate UBR5 and to promote malignancy of triple-negative breast cancer
点击查看 >>
Author：
Guohua Gong, Jikai She, Danni Fu, Dong Zhen, Bin Zhang
IF：
5.9420
Publish_to：
American Journal of Cancer Research
PMID：
35812044
High-Throughput Profiling of Cas12a Orthologues and Engineered Variants for Enhanced Genome Editing Activity
点击查看 >>
Author：
Dan Zhu, Junyi Wang, Di Yang, Jianzhong Xi, Juan Li
IF：
5.9240
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
34948095
Zebularine potentiates anti-tumor immunity by inducing tumor immunogenicity and improving antigen processing through cGAS-STING pathway
点击查看 >>
Author：
Zhang Yong, Zhao Heng, Deng Weili, Lai Junzhong, Sang Kai, Chen Qi
IF：
5.9000
Publish_to：
Communications Biology
PMID：
38755254
Adeno-associated virus-delivered alpha synuclein inhibits bladder cancer growth via the p53/p21 signaling pathway
点击查看 >>
Author：
Wu Zhengcun, Xia Chengxing, Zhang Chao, Tang Donghong, Liu Feineng, Ou Yitian, Gao Jiahong, Yi Hongkun, Yang Delin, Ma Kaili
IF：
5.8540
Publish_to：
CANCER GENE THERAPY
PMID：
35064206
Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription
点击查看 >>
Author：
Ningning Zhao, Fan Wang, Zhengjie Kong, Yingli Shang
IF：
5.8180
Publish_to：
Viruses-Basel
PMID：
35891444
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression
点击查看 >>
Author：
Zhou Jie, Li Peiwei, Zhao Xiaogang, Zhao Yuanhao, Luo Junwen, Deng Yupeng, Jiang Ning, Xiao Zhaohua, Zhang Wenhao, Zhou Yongjia, Zhao Jiangfeng, Li Peichao, Li Yuliang, Tian Zhongxian
IF：
5.8000
Publish_to：
RESPIRATORY RESEARCH
PMID：
37953225
Targeting MDK Abrogates IFN-γ-Elicited Metastasis inCancers of Various Origins
点击查看 >>
Author：
Luyu Zheng, Qun Liu, Ruijun Li, Shibin Chen, Jingyu Tan, Lina Li, Xichen Dong, Changzhi Huang, Tao Wen, Jian Liu
IF：
5.7380
Publish_to：
Frontiers in Oncology
PMID：
35747815
Nanobody-armed T cells endow CAR-T cells with cytotoxicity against lymphoma cells
点击查看 >>
Author：
Wang Hongxia, Wang Liyan, Li Yanning, Li Guangqi, Zhang Xiaochun, Jiang Dan, Zhang Yanting, Liu Liyuan, Chu Yuankui, Xu Guangxian
IF：
5.7220
Publish_to：
Cancer Cell International
PMID：
34429118
Evaluation of biomechanical properties and biocompatibility: are partially absorbable cords eligible for anterior cruciate ligament reconstruction
点击查看 >>
Author：
Fei Xu, Yanlin Li, Yang Yu, Guoliang Wang, Guofeng Cai
IF：
5.7000
Publish_to：
Frontiers in Bioengineering and Biotechnology
PMID：
37854884
Pim-2 kinase inhibits inflammation by suppressing the mTORC1 pathway in atherosclerosis
点击查看 >>
Author：
Minqi Liao, Feng Hu, Zhiqiang Qiu, Juan Li, Chahua Huang, Yan Xu, Xiaoshu Cheng
IF：
5.6820
Publish_to：
Aging-US
PMID：
34547720
Extracellular vesicles derived from M2 microglia reduce ischemic brain injury through microRNA-135a-5p/TXNIP/NLRP3 axis
点击查看 >>
Author：
Liu Yue, Li You-Ping, Xiao Li-Min, Chen Li-Ke, Zheng Su-Yue, Zeng Er-Ming, Xu Chun-Hua
IF：
5.6620
Publish_to：
LABORATORY INVESTIGATION
PMID：
33875790
FTO Sensitizes Oral Squamous Cell Carcinoma to Ferroptosis via Suppressing ACSL3 and GPX4
点击查看 >>
Author：
Ziyi Wang, Hongyu Li, Hongshi Cai, Jianfeng Liang, Yaoqi Jiang, Fan Song, Chen Hou, Jinsong Hou
IF：
5.6000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
38003537
JunB condensation attenuates vascular endothelial damage under hyperglycemic condition
点击查看 >>
Author：
Ren Xuxia, Cui Zexu, Zhang Qiaoqiao, Su Zhiguang, Xu Wei, Wu Jinhui, Jiang Hao
IF：
5.5000
Publish_to：
Journal of Molecular Cell Biology
PMID：
38140943
Smurf1 silencing restores PTEN expression that ameliorates progression of human glioblastoma and sensitizes tumor cells to mTORC1/C2 inhibitor Torin1
点击查看 >>
Author：
Qin Xia, Wenxuan Li, Sakhawat Ali, Mengchuan Xu, Yang Li, Shengzhen Li, Xinyi Meng, Liqun Liu, Lei Dong
IF：
5.4580
Publish_to：
iScience
PMID：
34917902
SUMOylation mediates the disassembly of the Smad4 nuclear export complex via RanGAP1 in KELOIDS
点击查看 >>
Author：
Xiaohu Lin, Qianqian Pang, Jie Hu, Jiaqi Sun, Siya Dai, Yijia Yu, Jinghong Xu
IF：
5.3000
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
36916534
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure
点击查看 >>
Author：
Liu Yang, Liu Peng, Hu Yajie, Cao Yu, Lu Jingjing, Yang Yuying, Lv Hongming, Lian Shuai, Xu Bin, Li Shize
IF：
5.2460
Publish_to：
Frontiers in Molecular Biosciences
PMID：
34395524
CircMYOF triggers progression and facilitates glycolysis via the VEGFA/PI3K/AKT axis by absorbing miR-4739 in pancreatic ductal adenocarcinoma
点击查看 >>
Author：
Zheng Dandan, Huang Xianxian, Peng Juanfei, Zhuang Yanyan, Li Yuanhua, Qu Junchi, Zhang Shineng, Huang Fengting
IF：
5.2410
Publish_to：
Cell Death Discovery
PMID：
34811346
Oxidized phospholipids facilitate calcific aortic valve disease by elevating ATF4 through the PERK/eIF2α axis
点击查看 >>
Author：
Xiaohua Zhu, Linjie Yang, Xu Han, Chen Huang, Gongcheng Huang, Tingju Wei, Liliang Shu, Jing Xu
IF：
5.2000
Publish_to：
Aging-US
PMID：
37462732
The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma
点击查看 >>
Author：
Ke Huang, Huihui Wang, Jia Xu, Ruiming Xu, Zelin Liu, Yi Li, Zhaoqing Xu
IF：
5.1680
Publish_to：
Biology-Basel
PMID：
35892971
Chlormequat Chloride Inhibits TM3 Leydig Cell Growth via Ferroptosis-Initiated Inflammation
点击查看 >>
Author：
Xiaoxia Wang, Chenping Kang, Wanqian Guo, Haoran Zhang, Qianqian Xiao, Weidong Hao
IF：
5.1000
Publish_to：
Cells
PMID：
38891111
Carcinoma-associated fibroblasts release microRNA-331-3p containing extracellular vesicles to exacerbate the development of pancreatic cancer via the SCARA5-FAK axis
点击查看 >>
Author：
Yadong Han, Xu Qian, Teng Xu, Yang Shi
IF：
4.8750
Publish_to：
CANCER BIOLOGY & THERAPY
PMID：
35510828
Long non-coding RNA COX7C-5 promotes hepatocellular carcinoma progression via miR-581/ZEB2 axis
点击查看 >>
Author：
Yantin Lin, Fei Wang, Yue Zhong, Niang Mei Cheng, Jiahui Xiong, Xiaoyuan Zheng, Yang Zhou, Shaodong Gao, Fang Li, Yingchao Wang, Xiaoyu Yang, Bixing Zhao
IF：
4.8500
Publish_to：
CELLULAR SIGNALLING
PMID：
36273755
UCHL1 aggravates skin fibrosis through an IGF-1-induced Akt/mTOR/HIF-1α pathway in keloid
点击查看 >>
Author：
Chipeng Guo, Lizhu Liang, Jingbin Zheng, Yang Xie, Xiaonan Qiu, Guozhen Tan, Jingang Huang, Liangchun Wang
IF：
4.8000
Publish_to：
FASEB JOURNAL
PMID：
37256780
MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation
点击查看 >>
Author：
Bingjie Cai, Min Li, Yunpeng Zheng, Yakun Yin, Fangcao Jin, Xuyang Li, Juan Dong, Xiaoyan Jiao, Xiaojun Liu, Kun Zhang, Dongqin Li, Junmin Wang, Guangwen Yin
IF：
4.7930
Publish_to：
HUMAN GENE THERAPY
PMID：
35171714
PPM1G promotes the progression of lung adenocarcinoma by inhibiting p38 activation via dephosphorylation of MEK6
点击查看 >>
Author：
Chen Jingying, Li Jizhuo, Sun Hong, Hu Tianyi, Wang Yameng, Kang Guoqi, Cao Mingya, Li Xia
IF：
4.7410
Publish_to：
CARCINOGENESIS
PMID：
36349938
IGFL2-AS1-induced suppression of HIF-1α degradation promotes cell proliferation and invasion in colorectal cancer by upregulating CA9
点击查看 >>
Author：
Mengdi Qin, Qiang Liu, Wei Yang, Qiaofeng Wang, Zheng Xiang
IF：
4.7110
Publish_to：
Cancer Medicine
PMID：
36537608
7-Hydroxycoumarin and its conjugated metabolites interact with organic anion transporters 1 and 3 in vitro and in vivo
点击查看 >>
Author：
Lijun Luo, Yongchun Chang, Weilin Zhang, Xiao Liu, Junpu Ge, Jieyi Chen, Yan Li, Dan Zhang, Li Sheng
IF：
4.7000
Publish_to：
CHEMICO-BIOLOGICAL INTERACTIONS
PMID：
39481674
Tumor specificity of WNT ligands and receptors reveals universal squamous cell carcinoma oncogenes
点击查看 >>
Author：
Chen Cheng, Luo Lunan, Xu Changling, Yang Xia, Liu Ting, Luo Jingyue, Shi Wen, Yang Lu, Zheng Yi, Yang Jing
IF：
4.6380
Publish_to：
BMC CANCER
PMID：
35850748
Chlorogenic acid protects against myocardial ischemia每reperfusion injury in mice by inhibiting Lnc Neat1/NLRP3 inflammasome-mediated pyroptosis
点击查看 >>
Author：
Chai Xin, Liang Zhengwei, Zhang Junshi, Ding Jing, Zhang Qian, Lv Sha, Deng Yazhu, Zhang Rongrui, Lu Deqin
IF：
4.6000
Publish_to：
Scientific Reports
PMID：
37853132
Inhibition of MDFI attenuates proliferation and glycolysis of Helicobacter pylori-infected gastric cancer cells by inhibiting Wnt/β-catenin pathway
点击查看 >>
Author：
Chen Mi, Yan Zhao, Li Ren, Dan Zhang
IF：
4.4730
Publish_to：
CELL BIOLOGY INTERNATIONAL
PMID：
36116024
Proteomic Analysis of Plasma sEVs Reveals That TNFAIP8 Is a New Biomarker of Cell Proliferation in Diabetic Retinopathy
点击查看 >>
Author：
Jing Xiao, Hui Zhang, Fuhua Yang, Mengran Xiao, Lei Zhou, Rongguo Yu, Xianfeng Shao, Vicki Ea, Lin Su, Xiaomin Zhang, Xiaorong Li
IF：
4.4660
Publish_to：
JOURNAL OF PROTEOME RESEARCH
PMID：
33594895
Electroporation-based Easi-CRISPR yields biallelic insertions of EGFP-HiBiT cassette in immortalized chicken oviduct epithelial cells
点击查看 >>
Author：
Lingkang Liu, Jinyu Wei, Chen Chen, Qianxue Liang, Boyong Wang, Wende Wu, Gonghe Li, Xibang Zheng
IF：
4.4000
Publish_to：
POULTRY SCIENCE
PMID：
37806084
The ubiquitin ligase RNF2 stabilizes ERα and modulates breast cancer progression
点击查看 >>
Author：
Yuan Lei, Li Xin, Yang Huijie, Li Huixiang
IF：
4.3740
Publish_to：
Human Cell
PMID：
36271315
LncRNA H19 sponges miR-103-3p to promote the high phosphorus-induced osteoblast phenotypic transition of vascular smooth muscle cells by upregulating Runx2
点击查看 >>
Author：
Wei Zhou, Qingyan Feng, Meijuan Cheng, Dongxue Zhang, Jingjing Jin, Shenglei Zhang, Yaling Bai, Jinsheng Xu
IF：
4.3150
Publish_to：
CELLULAR SIGNALLING
PMID：
34923106
TRPM2 knockdown attenuates myocardial apoptosis and promotes autophagy in HFD/STZ-induced diabetic mice via regulating the MEK/ERK and mTORC1 signaling pathway
点击查看 >>
Author：
Hu Feng, Lin Chaoyang
IF：
4.3000
Publish_to：
MOLECULAR AND CELLULAR BIOCHEMISTRY
PMID：
38308007
Reduced hepatic AdipoR2 by increased glucocorticoid mediates effect of psychosocial stress to elevate serum cholesterol
点击查看 >>
Author：
Qi Wei Guo, Jia Lin, Yi Lin Shen, Yan Jiang Zheng, Xu Chen, Mi Su, Ji Cheng Zhang, Jin Hua Wang, Hui Tang, Guo Ming Su, Zheng Ke Li, Ding Zhi Fang
IF：
4.1000
Publish_to：
MOLECULAR AND CELLULAR ENDOCRINOLOGY
PMID：
38815796
Lnc-PLA2G4A-4 facilitates the progression of hepatocellular carcinoma by inducing versican expression via sponging miR-23b-3p
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Author：
Jiahui Xiong, Yongping Lai, Niangmei Cheng, Jizhe Liu, Fei Wang, Xiaoyuan Zheng, Yingchao Wang, Qiuyu Zhuang, Yantin Lin, Jingfeng Liu, Yixuan Yang, Bixing Zhao, Xiaoyu Yang
IF：
4.0000
Publish_to：
Heliyon
PMID：
37554815
Semaphorin 4D is a potential biomarker in pediatric leukemia and promotes leukemogenesis by activating PI3K/AKT and ERK signaling pathways
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Author：
Hongchao Jiang, Jiaolian Tang, Lijuan Qiu, Zhen Zhang, Shulan Shi, Li Xue, Liyue Kui, Tilong Huang, Weiwei Nan, Bailing Zhou, Canchun Zhao, Ming Yu, Qiangming Sun
IF：
3.9060
Publish_to：
ONCOLOGY REPORTS
PMID：
33649851
YAP1-activated ZNF131 promotes hepatocellular carcinoma cell proliferation through transcriptional regulation of PAIP1
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Author：
Guozhi Yin, Siying Jia, Youju Zhang, Yao Xian, Yong Guo, Qingguang Liu
IF：
3.9000
Publish_to：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
PMID：
38341068
Shensu IV prevents glomerular podocyte injury in nephrotic rats via promoting lncRNA H19/DIRAS3-mediated autophagy
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Author：
Huang Yong, Huang Yaqian, Zhou Yehua, Cheng Jie, Wan Chanjun, Wang Maohong, Pi Chiheng, Wu Guoqing, Song Weiguo
IF：
3.8400
Publish_to：
BIOSCIENCE REPORTS
PMID：
33881140
RNA binding motif protein 3 (RBM3) promotes protein kinase B (AKT) activation to enhance glucose metabolism and reduce apoptosis in skeletal muscle of mice under acute cold exposure
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Author：
Liu Yang, Shi Hongzhao, Hu Yajie, Yao Ruizhi, Liu Peng, Yang Yuying, Li Shize
IF：
3.8270
Publish_to：
CELL STRESS & CHAPERONES
PMID：
36149580
Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids
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Author：
Guoyun Bi, Xuan Zhang, Weihong Li, Xin Lu, Xu He, Yaqiong Li, Rixing Bai, Haiyan Zhang
IF：
3.8000
Publish_to：
Cell Reports Methods
PMID：
38749443
E2F2 enhances the chemoresistance of pancreatic cancer to gemcitabine by regulating the cell cycle and upregulating the expression of RRM2
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Author：
Liu Qianfan, Song Chunzhuo, Li Junjun, Liu Meng, FU Liyue, Jiang Jiuliang, Zeng Zhirui, Zhu Haitao
IF：
3.7380
Publish_to：
MEDICAL ONCOLOGY
PMID：
35716217
Clonorchis sinensis Promotes Intrahepatic Cholangiocarcinoma Progression by Activating FASN-Mediated Fatty Acid Metabolism
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Author：
Xiaoxue Ren, Yanqing Wu, Tongtong Song, Qingxia Yang, Qianying Zhou, Jie Lin, Lixia Xu, Bangde Xiang, Zebin Chen, Ying Zhang
IF：
3.7000
Publish_to：
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
PMID：
39806791
Chaperones Hsc70 and Hsp70 play distinct roles in the replication of bocaparvovirus minute virus of canines
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Author：
Jianhui Guo, Yan Yan, Jinhan Sun, Kai Ji, Zhiping Hei, Liang Zeng, Huanzhou Xu, Xiang Ren, Yuning Sun
IF：
3.6000
Publish_to：
MOLECULAR MICROBIOLOGY
PMID：
38629786
Tenascin C Promotes Glioma Cell Malignant Behavior and Inhibits Chemosensitivity to Paclitaxel via Activation of the PI3K/AKT Signaling Pathway
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Author：
Zhang Qingping, Xu Binchu, Hu Fulan, Chen Xianjin, Liu Xinmin, Zhang Qinghua, Zuo You
IF：
3.4440
Publish_to：
JOURNAL OF MOLECULAR NEUROSCIENCE
PMID：
33876384
LHPP suppresses proliferation, migration, and invasion in hepatocellular carcinoma and pancreatic cancer by inhibiting EGFR signaling pathway
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Author：
Zhu Haitao, Song Chunzhuo, Li Junjun, Liu Qianfan, Liu Meng, Fu Liyue
IF：
3.4000
Publish_to：
MEDICAL ONCOLOGY
PMID：
37522936
Transcriptome analysis of long non-coding RNAs reveals NR_015556 lncRNA is a novel regulator for adipocyte differentiation
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Author：
Changqing Zuo, Yaqiong Pan, Dan Leng, Xiuju Chen, Fanghongniu Dong, Zhanying Lin, Zhong Dai, Zonggui Wang
IF：
3.3220
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
35231655
Hypermethylation-Mediated lncRNA MAGI2-AS3 Downregulation Facilitates Malignant Progression of Laryngeal Squamous Cell Carcinoma via Interacting With SPT6
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Author：
Jiantao Wang, Chuan Yang, Huan Cao, Jianwang Yang, Wenxia Meng, Miaomiao Yu, Lei Yu, Baoshan Wang
IF：
3.3000
Publish_to：
CELL TRANSPLANTATION
PMID：
36852700
Knockdown of HDAC10 inhibits POLE2-mediated DNA damage repair in NSCLC cells by increasing SP1 acetylation levels
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Author：
Hua Guo, Hui Ren, Kun Han, Jianying Li, Yu Dong, Xuan Zhao, Chunqi Li
IF：
3.2000
Publish_to：
PULMONARY PHARMACOLOGY & THERAPEUTICS
PMID：
37657752
BTG2 acts as an inducer of muscle stem cell senescence
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Author：
Baozhou Peng, Yihan Chen, Yaning Wang, Yixi Fu, Xinrui Zeng, Hanmeng Zhou, Zibaidan Abulaiti, Shuaiyu Wang, Hongbo Zhang
IF：
3.1000
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
37269593
Knockdown of MIR9‑3HG inhibits proliferation and promotes apoptosis of cervical cancer cells by miR‑498 via EP300
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Author：
Fang Li, Ying Liang, Pian Ying
IF：
2.9520
Publish_to：
Molecular Medicine Reports
PMID：
34468010
Hydroxysafflor Yellow A Promotes HaCaT Cell Proliferation and Migration by Regulating HBEGF/EGFR and PI3K/AKT Pathways and Circ_0084443
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Author：
Zhang Yue, Xiao Yan-wei, Ma Jing-xin, Wang Ao-xue
IF：
2.9000
Publish_to：
Chinese Journal of Integrative Medicine
PMID：
37688744
PRODH Regulates Tamoxifen Resistance through Ferroptosis in Breast Cancer Cells
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Author：
Ping Zhang, Na Qian, Haigen Lai, Shu Chen, Kuaiying Wu, Xiaofeng Luo, Bo Lei, Mengqi Liu, Jiajun Cui
IF：
2.8000
Publish_to：
Genes
PMID：
39457440
Identification of a novel circ_0018289/miR-183-5p/TMED5 regulatory network in cervical cancer development
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Author：
Zou Heng, Chen Huijia, Liu Shuaibin, Gan Xiaoling
IF：
2.7540
Publish_to：
World Journal of Surgical Oncology
PMID：
34404391
Redifferentiation of genetically modified dedifferentiated chondrocytes in a microcavitary hydrogel
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Author：
Yao Yongchang, Chen Ke, Pan Qian, Gao Hui, Su Weixian, Zheng Shicong, Dong Weiqiang, Qian Dongyang
IF：
2.7000
Publish_to：
BIOTECHNOLOGY LETTERS
PMID：
38523201
Suspension state affects the stemness of breast cancer cells by regulating the glycogen synthase kinase-3β
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Author：
Lini Chen, Yonggang Lv
IF：
2.6000
Publish_to：
TISSUE & CELL
PMID：
37683322
The Role of miR-34c-5p in Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells
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Author：
Bin Liu, Wei Gan, Zhang Jin, Meng Wang, Guopeng Cui, Hongyu Zhang, Huafu Wang
IF：
2.5000
Publish_to：
International Journal of Stem Cells
PMID：
33906980
Resolvin D1 Induces mTOR-independent and ATG5-dependent Autophagy in BV-2 Microglial Cells
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Author：
Pan Shang-wen, Hu Li-sha, Wang Han, Li Rui-ting, He Ya-jun, Shang You, Dai Zhong-liang, Chen Li-xin, Xiong Wei
IF：
2.4000
Publish_to：
Current Medical Science
PMID：
37924386
PK15 cell line stably overexpressing IL2 enhances PCV2 replication
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Author：
Zhang Xuliang, Zhao Yingfeng, Ma Chang, You Jinwei, Dong Min, Yun Shifeng, Liu Jie
IF：
2.3320
Publish_to：
VIRUS GENES
PMID：
33389634
eIF4E-eIF4G complex inhibition synergistically enhances the effect of sorafenib in hepatocellular carcinoma
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Author：
Chao Fang, Haishen Xie, Jun Zhao, Weichen Wang, Hui Hou, Bin Zhang, Dachen Zhou, Xiaoping Geng
IF：
2.2480
Publish_to：
ANTI-CANCER DRUGS
PMID：
33783376
Therapeutic potential of exosome derived from hepatocyte growth factor-overexpressing adipose mesenchymal stem cells in TGFβ1-stimulated hepatic stellate cells
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Author：
Wang Jin, Ye Weikang, Jiang Ming, Zhou Yinong, Zheng Jie
IF：
2.2000
Publish_to：
CYTOTECHNOLOGY
PMID：
38495297
The Deubiquitinase USP22-Stabilized COL17A1 Promotes Lung Adenocarcinoma Progression
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Author：
Guangxi Chen, Dandan Du, Haihua Wang, Huifeng Li
IF：
1.9000
Publish_to：
Clinical Respiratory Journal
PMID：
39143031
Protocol for generating brain metastatic tumor cells through repeated intracardiac injections in mice
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Author：
Li Wang, Xiaoxia Chen, Chengtao Dong, Shengqi Yin, Li Liang, Aidong Zhou
IF：
1.3000
Publish_to：
STAR Protocols
PMID：
39708324
Mechanism underlying the regulation of lncRNA ACTA2-AS1 on CXCL2 by absorbing miRNA-532-5p as ceRNA in the development of ovarian cancer
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Author：
Yu Li, Zhiyou Yang, Jing Chen
IF：
0.9000
Publish_to：
International Journal of Clinical and Experimental Pathology
PMID：
34093945
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请问聚凝胺（货号H8761）能在常温下放置多久？我把其放置在常温下长达两天，还能用吗?2023-08-09 18:56:01
您好，使用后尽快-20°保存，常温放置后建议观察试剂性状有无明显变化，若无明显改变可进行预实验进行检测。